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Biomedical subjects

S Matányi

Publications and source records attributed to S Matányi.

14 recordsLinked to original sources

Urodynamic investigation of women operated on for genuine stress incontinence.

Anterior colporrhaphy (Kelly-Stoeckel suture) was performed on 22 women suffering from grade-I or grade-II genuine stress incontinence. Urodynamic investigation was performed on every patient before surgery and 6 months postoperatively. 21 patients were cured and 1 patient improved. After operation the functional urethral length was increased by 28.8%, and urethrovesical pressure transmission was improved by 22.9%. Maximum urethral closure pressure decreased postoperatively by 21.1%. Pressure transmission was clearly improved by the surgical intervention and urinary continence was restored in spite of the fact that maximal urethral closure pressure decreased. Based on these results it is suggested to consider performing anterior colporrhaphy in cases of weak urethral closure pressure, because of the increased risk of worsening the complaints of these patients.

Adult↗

[Urinary incontinence in pregnancy and puerperium].

In a study of 421 patients questioned in immediate post-partum the author observed a urinary incontinence during pregnancy in 30.6% of the cases, this figure is comparable to those found in literature. The post-partum incontinence was not observed when forceps, vacuum extraction or caesarean section have been used. The urinary disorders observed during post-partum regresses spontaneously in 68% of the cases. However, one can ask the question on whether it is not reveal a light pelvic alteration which could cumulate at each delivery, so it would be necessary to use a pelvic training.

Female↗

Factors affecting the cold transfer during cryotherapy.

Cryotherapy of the cervix was made in 40 patients for chronic cervicitis, and the thickness of the ice zone around the probe was measured in function of treatment time, under standard cooling conditions. The pace of growth of the ice zone allowed the author to draw conclusions as to the conductivity of the studied tissue. It was established that in the study-group, the patient's age and their histories of abortions did not influence the cold transfer significantly. The difference between the average values of ice zone thickness measured in the groups of nulliparae and multiparae was, however, significant. Findings have shown that the spread of cold in the cervical tissue in nulliparous women is better than in multiparae and so a greater efficacy of cryotherapy can be expected in nulliparae.

Adult↗

The use of nonspecific esterase in assessing the effectivity of cryotherapy on the uterine cervix.

Cryotherapy of the uterine cervix can produce tissue damage of various depths. It is very important to be familiar with the extent of tissue damage in standardizing the treatment and assessing its effect. In the present work nonspecific esterase reaction was applied for the early study of tissue damage. It was found that this method can be used with benefit in the early assessment of the effect of freezing. The enzyme reaction was primarily a sensible marker of cell damage in the cervical cells.

Adult↗

Ultrastructural alterations in the ectocervical epithelium after cryotherapy.

The central problem of the cryosurgery of the uterine cervix in gynaecological practice is the extension in depth of the tissue impairment. The ultrastructural alterations were studied in the surgical material of portioplasties performed two hours after cryotherapy of the non-malignant ectocervical changes of fertile women. For control, the unfrozen regions of the same cervix were used. The vacuolization of the cytoplasm and partial fragmentation of the mitochondria appear to be detectable and reversible changes. Parallelly, severe irreversible nuclear impairments can be demonstrated in the basal and parabasal layers of the cervical epithelium. The relative connective tissue insensitivity, in contrast to the damage of the epithelium, verifies the advantage of cryosurgery in the therapeutic applicability.

Cervix Uteri↗

Change of tissue temperature of the uterine cervix during double freezing.

The tissue temperature of the uterine cervix was measured at a distance of 5 mm from the cryoprobe by using the double-phase freezing technique. It was established that by this method a deeper cold effect and tissue necrosis can be achieved than by one-phase freezing. In view of the linear extension and the extension in depth of CIN, as well as of its fairly frequent localization in the transformational zone, the method is mainly suitable for curing minor CIN lesions of young patients.

Body Temperature↗

Cryotherapy during pregnancy.

Benign cervical alterations causing complaints in 44 pregnant women were cured by cryosurgery in all three trimesters of their pregnancy. Recovery resulted in 41 cases after a single and in three extensive chondylomatous changes, after two treatments. The painless out-patient treatment did not influence pregnancy and the course of delivery. Cryosurgery has advantages over traditional surgical interventions, or using chemical caustic agents and it can be applied throughout pregnancy.

Adult↗

[Experiences in treatment of urinary incontinence in the female by electrostimulation].

Electrostimulation-treatment was carried out in 47 female patients suffering from urinary stress incontinence. A special electrode-pair was applicated in the vagina under the bladder neck. The electrostimulation lasted for 8 hours daily through 3 to 8 days on one hand, and on the other hand for 24 hours 3 to 5 times successively. In order to specify the cases and to perform the urodynamics a uroflow-cystometer by Wolf was used. The classification of the stress incontinence occurred by the Ingelman-Sundberg scheme. Rate of successfully treated patients depended on the length of time and degree of incontinence, furthermore on the extent of anatomical alteration. Following the electrostimulation 20 patients became symptomless (42 per cent), in 17 cases the complaints decreased and in 10 cases the treatment proved to be inefficient. Authors suggest that like other conservative measures the vaginal electrostimulation can be applied as a treatment of some forms of urinary stress incontinence under in-patient service.

Adult↗

Temperature of the portio uteri in cryosurgical treatment.

The cryosurgical treatment of various benign changes in the uterine cervix has gained wide acceptance [4, 8, 15, 16, 17, 29]. The application of cryosurgery has widened the range of gynaecologic therapeutic methods. As all new methods, it could not entirely fulfil all expectations. The results of initial attempts at curing cancer or various precancerous diseases of the cervix were not wholly satisfying and, according to our present knowledge, the application of cryosurgery in such cases is not advisable except under certain specific circumstances [2, 3, 5, 7, 10, 12, 13, 14, 18, 24, 28, 33, 35]. The method promises excellent results in the treatment of chronic inflammation of the cervix resistant to conservative therapy, of condyloma acuminatum, ectopium, etc. [4, 8, 15, 17, 29, 30]. The present studies were undertaken in order to determine the relationship between the cooling velocity attained in cryosurgery and using Erbokryo-Amoils 40/a type device and nitric oxide. The extent of tissue destruction depends namely first of all on the velocity of cooling and then thawing. The thawing time is given as a function of the blood in the tissue. The cold temperature is not negligible causing tissue damage either.

Body Temperature↗

[Use of cryocoagulation in gynecology].

Cryocoagulation was performed in 101 cases, mainly when the lesions were on the surface of the vaginal portion or when endocervicitis resistant to conservative therapy was present. Healing was achieved in 95%, in 65% of the cases in 4 weeks, in 32% in 8 weeks. Cryocoagulation is painless and can be applied without anaesthesia even in out-patients. It is advisable to apply treatment a few days after the end of menstruation. No complications were observed. Pathologic lesions or extensive ruptures of the cervix are not suited for cryocoagulation and should be treated as before by surgical intervention.

Adult↗

Side effects and complications of cervical cryotherapy.

The side effects and complications of 1248 cervical cryosurgeries performed in the course of 12 years are scrutinized. The side effects (hypogastric discomfort, vascular reactions) are negligible, a profuse vaginal discharge should be reckoned with following the treatment.

Cryosurgery↗

Promotion of epithelialization of the uterine cervix surface following cryotherapy.

The vaginal application of sugar powder after cryotherapy considerably decreased the amount and duration of leukorrhea following cryotherapy of benign alterations of the uterine cervix. The time needed for epithelialization of the surface of the portio became shorter. The method is recommended for the decrease or elimination of the discomfort caused by post-cryotherapeutic leukorrhea.

Adolescent↗