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Biomedical subjects

S Matteoli

Publications and source records attributed to S Matteoli.

31 records · Page 2Linked to original sources
PubMed1981

[The effects of physical training and nifedipine on patients recovering from acute myocardial infarction (author's transl)].

10 patients recovering from acute myocardial infarction with stable symptomatology, underwent 3 subsequent ergometric trials: the first, basic, the second, after one month of practice on an ergometer bicycle and the third, with a longer period of training, after acute administration of nifedipine. The purpose of the study was to establish whether the administration of a drug such as nifedipine, acting principally on the after load, could further improve the working abilities of ischemic cardiopaths, already trained for muscular work. The results demonstrated that proper training can significantly increase the duration of muscular exercise, while the acute administration of 20 mg of nifedipine was not able to improve, to a greater degree, the working ability of patients who were already trained. The result was interpreted as being due to the inability of the trained organism to further increase the peripheral oxygen-saving mechanisms.

Adult↗
PubMed1978

Infarct as a stress agent: life history and personality characteristics in improved versus not-improved patients after severe heart attack.

Fifty-eight male subjects admitted to an intensive coronary care unit were interviewed and underwent psychometric testing on the second--third day after a severe heart attack (infarct). Seven-ten days following admission, the clinical condition of the patients was evaluated by the attending cardiological staff and rated on a three point scale. The patients were divided, on the basis of the clinical rating, into two groups: improved (N = 25) and non-improved (N = 33). Life history characteristics, MMPI personality profiles, and State-Trait anxiety scores were then compared for the two groups. The not-improved group showed the higher scores on almost all the MMPI scales, higher anxiety scores and more work-related problems than the improved group. Such data give some empirical support to the hypothesis that the physiological and hemodynamical conditon of the cardiac patient is in some way correlated with the patient's style of coping with stress, and his history of previous life stress situations.

Adaptation, Psychological↗
PubMedDate not supplied

Treatment of myocardial infarction: hypotensive effect of different thrombolytic agents.

The incidence of hypotension in patients treated with thrombolytic agents for myocardial infarction was investigated in a series of 71 patients, 17 treated with urokinase, 35 with rtPA and 19 with APSAC. Hypotension was observed in 23.5% of the first group, in 5.5% of the second, and in 42.10% of the third (p < 0.002 between rtPA and APSAC). In the inferior location hypotensive reaction was much more frequent than in anterior one (p < 007) especially if a right ventricular involvement was associated. Even if hypotension is a minor and generally harmless complication, it poses many practical problems, and its occurrence must be taken into account when choosing a fibrinolytic treatment.

Antihypertensive Agents↗
PubMedDate not supplied

[The "natural" history of ischemic cardiopathy, Incidence of coronary events in the follow-up of 114 ambulatory patients].

In the last decade advances in cardiovascular research improved remarkably our understanding of coronary heart disease. However many important problems are so far unresolved. In the present study we focused on the "natural" history of ischemic heart disease in a group of 114 patients. One hundred-seven patients had recent myocardial infarction, and seven suffered from angina. They were observed for a mean period of five years (one to 168 months). Forty-nine patients (42.9%) had no coronary events; sixty-five had angina, myocardial infarction or both. The myocardial infarction was however rare (five cases). The most frequent presentation of angina was stable and effort angina, which sometimes subsided after a period of presence. The classification of angina was often very difficult in cases of effort angina with very low threshold. No relevant differences were found between patients with and without coronary events according to age, sex, duration of follow-up, location of previous myocardial infarction. A significant difference was found in the prevalence of risk factors only for hypertension, which was more frequent in patients with coronary events. Smokers were more frequent in group without coronary events. In our opinion, the most interesting conclusion is that, almost half of these patients remained completely asymptomatic for a very long period.

Adult↗