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S Meisner

Publications and source records attributed to S Meisner.

28 records · Page 2Linked to original sources
PubMed1988

The Kaplan and Meier and the Nelson estimate for the probability of ulcer recurrence 10 and 15 years after parietal cell vagotomy.

The use of a nonparametric estimate from incomplete observations is demonstrated on ulcer recurrence 10-15 years after parietal cell vagotomy in 339 patients with duodenal ulcer. The median period of observation was 108 months (range: 1-197 months). Proven recurrent ulcer developed in 62 patients. The life-table method as described by Kaplan and Meier and Nelson's modification are demonstrated. The calculated risk of recurrence after 10 years was 23% (+/- 3.8%) and after 15 years was 27% (+/- 4.3%). The rate of recurrence seemed to decline toward the end of the trial time.

Duodenal Ulcer↗
PubMed1988

Susceptibility of Rorschach distress correlates to malingering.

This study examined whether faking depression can affect Rorschach variables associated with distress. Fifty-eight nondepressed undergraduates were randomly assigned to experimental and control groups of 29 subjects each. All subjects took the Minnesota Multiphasic Personality Inventory (MMPI) Depression Scale, Rorschach Inkblot Test, and Beck Depression Inventory (BDI) under standard administration procedures. Immediately before taking the Rorschach and BDI, experimental group subjects were: (a) instructed to fake depression, (b) provided with a clinical description of the disorder, and (c) offered a cash incentive for the most convincing test display of depression. These conditions increased scores on the BDI, p less than .0001, Morbid Special Score, p less than .05, Bl, p less than .005, and reduced R, p less than .05, but affected no determinants. Power to detect a clinically significant effect of faking on the sum of gray-black determinants was .99 (alpha = .05). Major implications are: (a) abnormal frequencies of determinants should not be attributed to malingering, and (b) Rorschach content measures of depression are affected by impression management strategies.

Adult↗
PubMed1984

Ulcer recurrence after parietal cell vagotomy for duodenal ulcer. A multivariate pattern recognition study.

The object of the study was to identify individual high-risk patients with regard to ulcer recurrence after parietal cell vagotomy for duodenal ulcer. The study comprises a multivariate analysis of 14 variables (age, sex, duration of symptoms, site of ulcer, pre- and post-operative acid secretion) for 37 patients with and 111 patients without recurrence 5-11 years after parietal cell vagotomy for duodenal ulcer. The data were analyzed using a supervised pattern recognition technique, SIMCA (Soft Independent Modeling of Class Analogy), which analyzes complex data as geometrical elements in a multidimensional space. We found no statistical difference between the patients with and without ulcer recurrence. Thus, no predictive value for the selection of patients liable to develop recurrent ulcer after parietal cell vagotomy was contained in the variables generally registered in current surgery.

Adult↗
PubMed1983

Antrectomy for recurrent ulcer after parietal cell vagotomy.

The results of antrectomy for recurrent ulcer after parietal cell vagotomy are reviewed. Eighteen patients underwent precise antrectomy between 6 months and 7 years after their primary operation. Fourteen patients were reconstructed with a gastroduodenostomy and 4 with a gastrojejunostomy. Eighteen patients were available for follow-up of between 18 months and 10 years. One patient (6.25 per cent) developed a recurrent ulcer 1 year after antrectomy. There was no operative mortality. Six patients (33 per cent) had minor complications in the immediate postoperative period, and one (5.5 per cent) had a major complication. According to Visick grading, 75 per cent had good or excellent results and 25 per cent poor results. Antrectomy following parietal cell vagotomy can be achieved with a low operative mortality, a low ulcer recurrence rate and a satisfactorily low incidence of post-gastrectomy problems.

Adult↗
PubMed1983

Ulcer recurrence two to twelve years after parietal cell vagotomy for duodenal ulcer.

An analysis is presented of the ulcer recurrence rate following parietal cell vagotomy in 333 patients with duodenal ulcer. The median period of observation for patients without ulcer recurrence was 54 months (range 1 to 128 months). Forty-two patients developed proven recurrent ulcer. The median period of freedom from recurrence was 33 months (range 3 to 113 months). Recurrent ulcer was suspected but not verified in an additional 12 patients. The calculated risk (by the life table method) of recurrence after 5 years was 13% (95% confidence limits 9-17), after 8 years 21% (14-28), and after 10 years 23% (15-31). The rate of recurrence remained constant throughout the study period. The analysis indicates a constant monthly recurrence risk of 0.23%. The patients with ulcer recurrence had a significantly lower reduction of peak pentapeptide acid output and higher rate of positive insulin test than patients without recurrence. The risk of recurrence did not depend on the location of the ulcer (duodenal bulb or pyloric-prepyloric area).

Adult↗
PubMedDate not supplied

Iron, but not folic acid, combined with effective antimalarial therapy promotes haematological recovery in African children after acute falciparum malaria.

Whether children with malarial anaemia should receive supplementation with iron or folic acid is uncertain. Therefore, the effects of supplementary treatment with iron or folic acid, given together with chloroquine or pyrimethamine-sulfadoxine (Fansidar), has been assessed in 600 Gambian children with uncomplicated falciparum malaria. After one month, haematological recovery was significantly better in the group treated with Fansidar than in the chloroquine-treated group (difference in mean haemoglobin level = 0.54 g/dL, P = 0.01). Children who received iron had a significantly better response than those given placebo (differences in mean haemoglobin level after one month and at dry season follow-up = 0.70 g/dL, P = 0.006, and 0.81 g/dL, P = 0.001, respectively). Iron supplementation was not associated with increased prevalence of malaria. Supplementation with folic acid did not improve the haematological response but, among children who received Fansidar, the treatment failure rate was significantly higher among those given folic acid than among those given placebo. Thus, supplementation with iron, but not folic acid, improves haematological recovery without increasing susceptibility to malaria.

Acute Disease↗