Decarboxylation of (1-14C) L-DOPA after intravenous and intraventricular administration to rats as measured by expired 14CO2.
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Animals↗
Biomedical subjects
S Mendelson
Publications and source records attributed to S Mendelson.
Effect of cane use on tibial strain and strain rates.
The effect of cane ambulation on hip biomechanics has been well studied, but its effect on tibial strains and strain rates is not known. To test the hypothesis that cane use may lower tibial strain and strain rates during walking, percutaneous axial extensometers were mounted on the right medial cortex of the midtibial diaphysis in seven male volunteers. In vivo peak-to-peak axial tibial strains and strain rates were measured for ipsilateral and contralateral cane usage and compared with a no cane control. Cane-assisted ambulation was not found to significantly lower strain magnitudes; however, tibial strain rates were significantly lowered by both ipsilateral and contralateral cane usage. We conclude that either ipsilateral or contralateral cane usage may be beneficial when lowering tibial strain rate is desired, such as in the treatment of tibia stress fracture or osteoarthrosis of the knee.
Adult↗
Anatomic considerations of the foot and leg in tibial hemimelia.
Five lower extremities from four patients with tibial hemimelia were available for dissection. Multiple tendon anomalies were present. The ankle articulation was found to have a nonfunctional uniplanar motion. Multiple coalitions of the osseous structures of the foot were found, with subtalar coalition the most common.
Amputation, Surgical↗
Comparison of low-dose subcutaneous heparin calcium and heparin sodium on ecchymosis formation.
Ecchymosis formation in patients receiving identical concentrations of heparin calcium or heparin sodium was compared in a double-blind study. Sixty-three patients admitted to a coronary-care unit with orders to receive heparin 5000 units subcutaneously every 12 hours were randomly assigned to receive either heparin calcium or heparin sodium. The drugs were administered identically. The presence and size of any ecchymosis were recorded by a single observer. The 44 patients on whom data were collected received 86 heparin sodium and 102 heparin calcium injections. While there were no difference between salts in the percentage of patients with documented ecchymosis , significantly more injection sites with ecchymosis were reported for the calcium salt. No significant difference was found in bruise size between the calcium and sodium salts of heparin. In a subgroup of patients who were not receiving other drugs known to prolong bleeding, there was no significant difference between the salts in the percentage of patients and injection sites with ecchymosis . The subcutaneous administration of heparin calcium resulted in significantly more injection sites with ecchymosis than did heparin sodium, but the size of the reported ecchymosis was not different between the two groups.
Aged↗