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Biomedical subjects

S Michieli

Publications and source records attributed to S Michieli.

At least 19 recordsLinked to original sources

Surgical lengthening of the mandible: a laboratory model.

Mandibular lengthening in mongrel dogs was evaluated in four animals. Extraoral approaches were used for mandibular exposure. Step osteotomies were performed on the buccal aspect and oblique osteotomies were performed on the lingual aspect of the mandible. The anterior fragment of the mandible was advanced 10 mm. A Dacron-urethane mesh tray, in the form of the mandible, was placed across the defect as a container of bone graft material and to help stabilize the segments. The bone graft material was harvested by aspirating the bone particles formed when the osteotomy cuts were made, thus creating a bone slurry which was placed within the implant. The results suggest that the use of the implant tray in conjunction with the bony slurry provided an appropriate physiologic setting for rapid new bone formation, restoring continuity to the defect.

Alveolar Ridge Augmentation↗

Preliminary histologic evaluation of a biocompatible mesh for tracheal reconstruction.

The purpose of this study was to evaluate a porous Dacron - urethane mesh tracheal prosthesis in large dogs with surgically created discontinuous defects of the cervical trachea. Some protheses were carbon coated in an attempt to improve biocompatibility. Histology was performed on 2 dogs. The mucosa regenerated entirely covering the prosthesis. Respiratory epithelium was formed over a large central portion of the tracheas.

Animals↗

Lengthening of mandibular body by gradual surgical-orthodontic distraction.

Lengthening of the mandibular body in two dogs was achieved with a technique that involved osteotomies and the use of an experimental orthodontic appliance; the approximation of the resected mandibular segments was maintained. There was no damage to the mandibular nerve and no conspicuous alterations of the nerve fibers. On the basis of results in experimental studies, the technique is proposed for use in correction of large discrepancies in length in persons with excessive mandibular retrusion.

Animals↗

[Controlled gradual lengthening of the mandible after osteotomy].

The procedures used to correct large discrepancies in the length of the mandibular body are described and experimental results are reported. The technique is realized using an orthodontic applicance that permits the progressive lengthening, after osteotomy of the mandibular body and also retains the approximation of the resected mandibular segments. Two dogs were used for the experimentation, achieving mandibular body lengthening of 5 and 15 millimeters. The bone neoformation was studied hystologically by means of microradiography and tetracyclines induced fluorescence. The surgical technique was carried out without damage to the mandibular nerve. The hystological examination shows no conspicous alteration of the nerve fibres.

Animals↗