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Biomedical subjects

S Milazzo

Publications and source records attributed to S Milazzo.

At least 37 records · Page 2Linked to original sources

[The laryngeal mask in ophthalmologic surgery. Criteria and limitations of use in adults (analysis of 57 cases)].

Clinical and physical data about laryngeal mask use in eye surgery were collected in 57 patients. We observed 4 failures which required endotracheal intubation, 3 leaks during operative field installation, 4 salvations but no laryngeal spasm and no cough. There were no significative differences between body weights in laryngeal mask groups no 3 and no 4. Insufflation pressures of patients without curarisation were more important. The duration of ventilation was not correlated with salivation, leaks or increase of insufflation pressure.

Adult↗

In vitro organotypic culture method to evaluate the biocompatibility of heparin-surface-modified intraocular lenses.

Using an organotypic culture method, we evaluated the biocompatibility of two kinds of intraocular lenses: conventional poly(methyl methacrylate) (PMMA) and heparin-surface-modified (HSM) PMMA. Chicken corneal endothelium from embryos incubated for 14 days was placed on an agar medium and covered with one of three types of materials: PMMA, HSM PMMA, and a control, Thermanox. Experiments at five different times measured cell migration, cell multiplication, and cell adhesion. Scanning electron microscopy showed a low level of corneal endothelial adhesion on the HSM IOL surface. There was a significant difference between the HSM and untreated lenses in migration surface and cell density, with the HSM lenses having better biocompatibility.

Animals↗

[Results of the treatment of acute endophthalmitis after cataract surgery].

Since 1980, the authors have observed 56 cases of endophthalmitis after cataract surgery which they classify into three groups: A. 18 cases of forms confined to the anterior segment, which just received medical treatment; B. 37 cases of more serious forms with vitreous abscess, treated by vitrectomy; C. 1 case of fulminant form which was eviscerated. The results of group B are better than those of group A: organic: 2.7% versus 11.1% of phtisis; functional: 73% of calculable visual acuity versus 66.6%, although the initial forms had been more severe. Vitrectomy, however causes some complications such as initial detachment (16.2%) cystoïd macular oedema (11%) and vascular complications (11%). However that may be, vitrectomy has several advantages: to collect a larger amount of vitreous liquid; to mechanically eliminate the pus; a faster functional rehabilitation by lightening of the vitreous.

Acute Disease↗

[Presymptomatic detection of familial colonic polyposis].

In familial adenomatous polyposis coli (APC) it is possible to detect APC carriers either by research of bilateral congenital hypertrophy of the retinal pigment epithelium (CHRPE) or by genetic diagnosis (APC gene is localized in 5q21). These detections were performed in 33 patients of four families with the same positivity for genetic typing (11 patients) or for CHRPE (11 patients) which thus avoided annual coloscopy.

Adenomatous Polyposis Coli↗

[Fundus oculi test in the detection of Gardner syndrome].

Gardner's syndrome is an adenomatous polyposis coli characterized by extracolonic manifestations such as congenital hypertrophy of retinal pigment epithelium. This inherited autosomal dominant disorder has a marked propensity to malignant transformation, so it is important to detect affected patients early. Ophthalmologic manifestations are simple, non invasive reliable and very sensitive. The gene responsible for this disorder was localized to the long arm of the fifth chromosome. The results of investigation in 3 families are reported herein and compared with the data of the literature.

Adolescent↗

[Functional results of cataract surgery with implantation in Fuchs' heterochromic cyclitis].

Cataract removal with implantation of an intraocular lens (IOL) was performed in 66 cases of Fuchs' heterochromic cyclitis. After an average postoperative follow-up of 40 months (6 months to 10 years, 81.6% of cases obtained visual acuity superior or equal to 5/10 (16.6% with a final visual acuity of 10/10). Thirty cases were analysed, 27 had satisfactory binocular vision. Two complications explained this limited visual performance: vitreal disorders observed in 45.5% of cases were responsible for visual acuity inferior or equal to 5/10 in 23% of cases, glaucoma observed in 12.1% of cases (3 cases were secondary to cataract surgery), 25% of these patients with glaucoma lost all visual acuity and 62.5% had a high intraocular pression uncontrolled by surgery (5 cases). Other risk factors were less important: loss of transparency of intraocular lens caused by precipitates observed in one case, Irvine-Gass syndrome and retinal detachment observed in one case. The restoration of satisfactory binocular vision justifies the risks of intraocular lens implantation in cases of Fuchs' heterochromic cyclitis.

Adolescent↗

Analysis of results in the treatment of peripheral retinoschisis in sex-linked congenital retinoschisis.

Curative and prophylactic treatment of peripheral retinoschisis has been studied over a period of 20 years in 60 cases of sex-linked congenital retinoschisis. Peripheral retinoschisis occurred in 36 of 120 eyes. In all, 12 severely affected eyes in children under 10 years of age underwent surgery (8 improvements and 4 aggravations) and 21 cases were photocoagulated (18 stabilisations and 3 aggravations that were subsequently treated by surgery); 6 cases were not treated. Aggravations after surgery or photocoagulation were consistently observed in the early post-operative follow-up period. An epidemiological study of these 60 patients demonstrated that bullous-phase peripheral retinoschisis occurs only in patients under 10 years of age, with a tendency to regress with age (no cases were reported in patients over 50 years of age). This study closely corroborates the findings of authors who think that this type of retinoschisis tends to improve spontaneously and that indications for prophylactic or curative treatment should be very carefully considered.

Adolescent↗

[Eales' syndrome and hypereosinophilia].

Authors report one case of a non typical Eales' disease associated to an hypereosinophily. None etiology was found nosology and physiopathology of Eales' syndrome and Eales' disease are still unclear. Main element of diagnosis is the discovery of a general pathology.

Adult↗

[Asteroid hyalitis: an uncommon complication of retinal telangiectasis].

The authors report a case of asteroid hyalosis which required a vitrectomy because of the decreased vision. The vitrectomy places in a prominent position an epi-macular membrane which has been peeling during the procedure and retinal vascular malformations like "telangiectasies" which are the starting point of other complications.

Adult↗

[Aspects of the tilted disk syndrome].

4 cases of tilted disc syndrome are reported. Two were associated with sellar or endocrine pathology, one had a particular aspect of chorioretinal atrophy, and the last had a thrombosis of the central vein of retina. The most commonly aspects of tilted disc syndrome are reported.

Adult↗

[Reticular macular dystrophy and Steinert disease].

We studied the macular lesions of 14 patients with myotonic dystrophy. 4 of them presented signs of reticula dystrophy of the macular pigmentary epithelium. We searched the association with other ocular modifications.

Adult↗

[Descending ocular myopathy--apropos of a case].

Descending ocular myopathy is a rare progressive disease characterized by bilateral ptosis, external ophthalmoplegia and progressive dystrophy of the proximal skeletal muscles. A case of descending ocular myopathy with post-operative corneal ulceration is reported. Mitochondrial abnormalities are found on skeletal muscle biopsy. Nosologic classification of this case is discussed.

Adult↗