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S Milea

Publications and source records attributed to S Milea.

29 records · Page 2Linked to original sources
PubMedDate not supplied

Further epidemiological investigations on subacute sclerosing panencephalitis (SSPE) in Romania.

The epidemiological study of 101 SSPE cases revealed the following aspects: a) an increase in the annual SSPE incidence, in relation to the improvement of detection possibilities; b) the preponderent involvement of male children and of children having experienced measles within the first 6-18 months of life; c) the high incidence of SSPE cases in families with several children, the patient being the 2nd or 3rd sibling; d) a mean interval of 50.1 +/- 32 months between acute measles and the onset of SSPE; e) the clustering of cases in terms of the epidemic year when acute measles had occurred. There were no modifications in SSPE epidemiology during the first 6 months after the initiation of mass antimeasles vaccination.

Adolescent↗
PubMedDate not supplied

Epidemiology of subacute sclerosing panencephalitis (SSPE) in Romania between 1976-1982.

The analysis of 415 SSPE cases detected between 1976-1982 pointed out a relatively high yearly incidence of this disease: 5-6 cases per 1 million inhabitants. Clusters of SSPE cases were observed in certain counties of Romania. The onset of SSPE occurred mostly at 6-7 years (only 6% of the cases were detected in children over 10 years of age); the mean duration of the interval between acute measles and SSPE onset was of 4-5 years. The following risk factors were made evident in the patients' past histories: male sex, acute measles experienced under the age of 1-2 years, existence of several siblings, long time intervals spent in the rural environment or in child communities, contact with domestic animals. During the first three years of its application on a national scale antimeasles vaccination had no effect on SSPE incidence.

Adolescent↗
PubMedDate not supplied

Data on the incidence of subacute sclerosing panencephalitis (SSPE) in Romania.

A programme for the active detection of SSPE cases hospitalized in the Clinic for Infantile Neuropsychiatry within the "Dr. Gh. Marinescu" Hospital, Bucharest, was initiated in 1975. The diagnosis relied on clinical, electroencephalographic and seroimmunological criteria. Thirty-three cases were sufficiently documented to be considered as SSPE (mean age on onset: 6.1 years; male/female ratio: 3.7). Clinical, immunological and epidemiological particularities resulting from this investigation are presented and epidemiological parameters of SSPE are discussed in relation to measles mortality data. The incidence of SSPE--a lethal persistent measles infection--points to the necessity of antimeasles vaccination.

Adolescent↗