Biomedical subjects

S Mizyed

Publications and source records attributed to S Mizyed.

2 recordsLinked to original sources

PubMed2001

Embracing C(60) with multiarmed geodesic partners.

1,3,5,7,9-Pentakis(4-methoxyphenylthio)corannulene (3), 1,3,5,7,9-pentakis(2-naphthylthio)corannulene (4), and 1,3,6,8-tetrakis(4-methoxyphenylthio)corannulene (5b) have been synthesized by chlorination of corannulene with ICl in CH(2)Cl(2) at 25 degrees C and subsequent nucleophilic aromatic substitution with the appropriate sodium thiophenolate in DMEU at 25 degrees C. (1)H NMR titration studies demonstrate that these novel bowl-shaped hosts form 1:1 complexes with C(60) in toluene-d(8) solution with association constants of 454, 368, and 280 M(-1), respectively.

Journal Article↗

PubMed2001

Synthesis of hexahomotrioxacalix[3]naphtalenes and a study of their alkali-metal cation binding properties.

The first syntheses of the C3-symmetrical and unsymmetrical hexahomotrioxacalix[3]naphthalenes 3 and 4, respectively, and the corresponding tert-butyl hexahomotrioxacalix[3]naphthalene 3a are reported. A convergent synthesis of the linear hexahomotrimer precursors 19 and 19a is described, but the direct synthesis of 3 and 3a can also be achieved from the monomers 20 and 20a, respectively. A limited study of the binding properties of alkali-metal cations by 3 or 3a using a picrate-CHCl3 extraction showed only weak abilities to bind with the cations examined.

Journal Article↗