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Biomedical subjects

S Moberg

Publications and source records attributed to S Moberg.

At least 19 recordsLinked to original sources
PubMed1997

Inclusive educational practices as perceived by prospective special education teachers in Estonia, Finland, and the United States.

A survey of 125 prospective special education teachers assessed perceptions and beliefs about inclusive education in Estonia, Finland, and the United States (Michigan). The attitudes toward inclusion were rather critical. The Estonians were the most critical group, the Finns the least critical. The meanings attached to a student with severe mental retardation were related to the educational setting assessed as the best for this student. The findings suggest that special educators perceptions about inclusion are related to the prevailing implementation of inclusive education. The results support also the idea that the meanings attached to a person with a disability are connected with behavioural intentions toward this person.

Child↗
PubMed1994

Inclusive education in Finland: present and future perspectives.

The movement to integrate special education students into normal school classes started to develop in Finland in the 1960s. At the same time, the number of students labeled "special" in the Finnish comprehensive school system exploded from 2% to 17% of all school children. Presently, 84% of all special education placements are part-time placements. Special schools and special classes comprise 15% of all special education placements, while full inclusion is only 1% of all special education placements. Some factors affecting the current integration of special students and the development of integration are discussed.

Adolescent↗
PubMed1991

The effect of omeprazole and ranitidine on ulcer healing, relief of symptoms, and incidence of adverse events in the treatment of duodenal ulcer patients.

In a Swedish double-blind multicenter study involving 143 patients, the new proton pump inhibitor omeprazole (30 mg taken as a single morning dose) was compared with ranitidine (400 mg b.i.d.). Clinical assessment and laboratory investigations were carried out at 2 and 4 weeks, and again at 6 weeks if patients had not healed earlier. Endoscopy was repeated at two-weekly intervals until the ulcer was healed. The patients in the two treatment groups were well matched prior to treatment. There was a higher ulcer healing rate in the omeprazole group (70%) than in the ranitidine group (55%) after two weeks of treatment. This difference reached statistical significance in 128 patients adhering to the protocol as shown by a logit model analysis with drug, ulcer size and smoking as the prognostic factors (p = 0.04). There were no major differences between the two treatment groups in terms of symptomatic relief. Both drugs were generally well tolerated, and the number of adverse events in the two treatment groups were similar. After healing, 127 patients entered a follow-up study, with endoscopy either after 6 months or on recurrence of symptoms. There was no significant difference between the two treatment groups, with the relapse frequency within 6 months being 39% in the omeprazole group and 47% in the ranitidine group. These results, with a 15 percentage points higher ulcer healing rate for omeprazole as compared with H2-receptor antagonists after two weeks, are in accordance with results reported in other studies.

Duodenal Ulcer↗
PubMed1987

Clinical strategy in the treatment of the irritable bowel syndrome.

The clinical strategy in the treatment of patients having the irritable bowel syndrome is especially important since it is often a psychosomatic disorder. The basis for clinical work with these patients depends very much on the doctor's attitude and the respect for the patients and their symptoms. Some practical guidelines with personal flavour from the work with patients having irritable bowels are discussed.

Colonic Diseases, Functional↗
PubMed1986

Ketoconazole treatment of 13 patients with chronic mucocutaneous candidiasis. A prospective 3-year trial.

Long-term results of initial ketoconazole treatment were evaluated in 13 patients with chronic mucocutaneous candidiasis followed up for 3 years. Six of them shared 11 endocrine or autoimmune disorders. All patients responded well to treatment but 1 dropped out owing to anxiety. Clinical and mycological clearing was achieved in 1-2 months for the mouth, 2 months for the skin, 3-4 months for paronychiae and 4-14 months for the nails. Bacterial infections persisted in 2 cases. After withdrawal of ketoconazole, 2 patients have remained in remission. Continuous therapy was required in 2 cases and the others were treated intermittently owing to recurrences of Candida stomatitis. Ketoconazole was well tolerated. An asymptomatic reversible increase of serum hepatic enzymes occurred in 1 case. Oral ketoconazole is the drug of choice for treatment of chronic mucocutaneous candidiasis but long-term observation is required.

Administration, Oral↗
PubMed1985

Long-term ketoconazole treatment of chronic acral dermatophyte infections.

Ketoconazole 200-400 mg was given once daily for a maximum period of 12 months to 31 patients with chronic (mean duration, 12 years) dermatophyte infections of the hands and/or feet. Griseofulvin had previously been withdrawn due to intolerance or lack of effect. All skin and nail infections improved clinically. Fifty percent of the patients with skin infections and 26% of those with nail infections became clinically clear and culture-negative. Six months later, relapses had occurred in 8 of 12 patients (67%) with cleared skin lesions, and in 2 of 5 (40%) with cleared nail infections. Ketoconazole was discontinued in one patient due to headache and in another due to asymptomatic transient elevation of hepatic laboratory tests. Ketoconazole is an alternative when a replacement for griseofulvin is required, provided the degree of disability justifies the risk of drug toxicity.

Female↗
PubMed1984

Omeprazole in Zollinger-Ellison syndrome. Effects of a single dose and of long-term treatment in patients resistant to histamine H2-receptor antagonists.

We studied the effect of omeprazole, a benzimidazole inhibitor of gastric acid secretion, in patients with Zollinger-Ellison syndrome. In five patients ingestion of 80 mg of omeprazole inhibited gastric acid secretion by 26 to 100 per cent after 6 hours and by 76 to 100 per cent after 24 hours. Seven patients were continuously treated with omeprazole once or twice daily for 8 to 19 months (average, 14). Six of these seven had symptoms that were resistant to high doses of histamine H2-receptor antagonists, and the seventh could not take high doses of cimetidine because of a possible drug-related increase in the serum creatinine concentration. Symptoms resolved in all patients within two weeks, and peptic lesions were healed at endoscopy after four weeks. All patients remained free of symptoms, and gastric acid secretion continued to be markedly inhibited by omeprazole therapy. We conclude that omeprazole is a potent and long-acting antisecretory drug in patients with Zollinger-Ellison syndrome and that it is effective in patients whose peptic-ulcer disease is relatively resistant to treatment with histamine H2-receptor antagonists. Its safety and effectiveness in long-term therapy remain to be assessed.

Adult↗
PubMed1984

Tinea capitis in the elderly. A report on two cases caused by Trichophyton tonsurans.

The clinical picture in tinea capitis due to Trichophyton tonsurans varies. In this report, 2 elderly female patients with T. tonsurans infections of the scalp mimicking eczema seborrhoeicum and discoid lupus erythematosus, respectively, are described. Recurrence of the infection in the first case was probably related to reduced fungal sensitivity to griseofulvin, as indicated in in vitro studies.

Aged↗
PubMed1983

A randomized trial of cadexomer iodine in decubitus ulcers.

Thirty-four patients with decubitus ulcers were studied in a randomized trial to compare topical cadexomer iodine with the standard decubitus ulcer treatments used in the participating hospitals. There was a significant reduction of ulcer area with both treatments within three weeks; however, eight of 16 patients treated with cadexomer iodine had a reduction of ulcer area of more than 50 per cent, compared with one of 18 patients treated with the standard treatment (P less than 0.01). Twenty-seven patients continued the same treatment for five more weeks, during which time six in the cadexomer iodine group healed, compared with one in the standard treatment group (P less than 0.05). Cadexomer iodine was superior to the standard treatment in removing pus and debris from the ulcer surface and in reducing pain at the ulcer site. It was found to be easy both to apply and to remove from the ulcers and did not stain skin or clothing. Transient smarting during the first hour after application was reported by three patients, and one patient complained of skin irritation. The results show that cadexomer iodine applied daily has a debriding effect on decubitus ulcers and accelerates healing.

Administration, Topical↗
PubMed1980

[Proctitis].

Explore the source record for details and available documents.

Humans↗
PubMed1980

Selective proximal vagotomy without drainage in the treatment of duodenal ulcer. The results after a standardization of the surgical technique. A five-year follow-up.

Selective proximal vagotomy without polyoroplasty has been shown to be a difficult operation to perform and some investigator have got a rather high frequency of recurrencies and operative complications. In an attempt to reduce the surgical failures a standardization of the operation has been undertaken. In the present material the long term results of a material operated upon with stardardized technique has been estimated. The operation resulted in a high reduction of the ability to secret acid. 90% of the patients had almost no side effects of the operation and 4.4% got a relapse. The relapses developed in patients with a negative postoperative insulin test. The prognostic value of the insulin test seems therefore doubtful.

Adult↗
PubMed1977

The effect of cimetidine in meal-stimulated gastric functions measured with a new method.

A new method to measure gastric functions after meal-stimulation without infusion of bicarbonate into the stomach is presented. Six healthy volunteers were investigated after stimulation of the gastric functions with a 300-ml fluid test meal with and without cimetidine infusion. Cimetidine reduced the acid output substantially but had no effect on gastric emptying.

Adolescent↗
PubMed1976

Gastric emptying and bile acid concentration in the duodenum after bypass operation of the small intestine because of obesity.

Gastric emptying was measured concomitantly with bile acid concentration in the duodenum in 9 patients operated upon with jejuno-ileal bypass. Two of them were cholecystectomized. The results of gastric emptying were compared with those of 7 healthy volunteers. The emptying rate was within normal limits, except for one cholecystectomized shunt-operated patient who had extremely low bile acid concentration in the duodenum.

Adult↗