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Biomedical subjects

S Mzabi-Regaya

Publications and source records attributed to S Mzabi-Regaya.

At least 19 recordsLinked to original sources

[Unilocular macrocystic serous cystadenoma of the pancreas: a morphologic variant to be considered].

Serous cystadenoma of the pancreas is a benign cystic tumor, which radiological diagnosis is easy in its typical microcystic variant. The macrocystic variant is uncommon and raises diagnostic problems with other macrocystic lesions of the pancreas such as pseudocysts and mucinous cystadenomas. We report the case of a young woman with a unilocular macrocystic serous cystadenoma of the pancreas which was identified on pathologic examination of the surgical specimen, after unconclusive abdominal ultrasound and CT-scan. This case describes an unusual clinical presentation of this cystic tumor and emphasizes that the diagnosis of such an entity is still based on pathological examination after cyst removal.

Abdominal Pain↗

[Buschke-Loewenstein giant condyloma in the perianal region with inguinal invasion: a case report].

The giant condyloma acuminatum of the perianal region is a tumor characterised by its large size with the propensity to infiltrate into deeper tissues, contrasting with a microscopically benign pattern. The evolution after malignant transformation of condyloma and lymph node invasion is rare. However it is exceptionally observed a lymph node invasion of microscopically benign condyloma acuminatum. The authors report a case of microscopically benign giant condyloma acuminatum of the perianal region associated with inguinal invasion, discovered in a 47 year-old man. Treatment consists in extensive surgery of the tumor and inguinal nodes, followed by a radiation therapy.

Anus Neoplasms↗

[Polymorphous low-grade adenocarcinoma of the accessory salivary glands--a case report].

A case of polymorphous low-grade adenocarcinoma of minor salivary gland is reported. This tumor was first described in two clinical case series in 1983. Before that time most of these neoplasms were diagnosed as benign salivary gland neoplasms (pleomorphic adenomas) or salivary malignant conditions (malignant pleomorphic adenomas, adenoid cystic carcinomas, papillary adenocarcinomas and adenocarcinoma not otherwise stated). This neoplasm, with few exceptions, originates in minor salivary gland tissues of the palates or buccal mucosa. It is characteristically slow to enlarge. Clinical reports show the neoplasm present for many years before diagnosis. The tumor have a variety of morphological patterns, a cytological uniformity and an infiltration into adjacent structures. The treatment is a wide local excision. Recurrences and lymph node metastases are rare.

Adenocarcinoma↗

[Endosalpingosis: apropos of a case of colonic localization].

The endosalpingosis is a benign affection which is in the most often asymptomatic. It means the presence of tubal mucosa in ectopic location; often in the tubal wall; the pelvic peritoneal and adjacent lymph node. We present here a colic endosalpingosis case with intestinal occlusion. We review in this purpose the literature, and discuss the etiopathogenicity. It shows that a previously tubal affection can have a great part in the birth of this pathology.

Colonic Diseases↗

[Fibro-inflammatory polyposis of the stomach: apropos of a case].

The stomach fibro-inflammatory-polyp is distinguished from the eosinophilic granuloma by some authors because of their geographic assessments. It is an inflammatory affection represented by a pseudo tumoral lesion. We present a case concerning a woman, 62 years old, who presented since 10 years a Biermer anaemia; a neoplastic affection was suspected, and then denied by histopathologic exam. We shall discuss the pathogenic and therapeutic data proposed by the literature. Recently, the treatment of this benign lesion consists in endoscopic resection. There no recurrence or malignant degeneration.

Anemia↗

[Malignant tumors of the stomach: apropos of 583 anatomo-clinical cases].

A retrospective study interesting 582 anatomoclinical cases of gastric malignant tumors was realised in two anatomo-pathological services of Tunis from 1970 to 1985. The average age of patients is 55 years old, with extensive ranges from 17 to 85 years old. The authors point out significative male predominance 64.6% of cases. The ulcered form is the most frequent, about 3.8% of macroscopic aspect cases. Among these last, the authors find 26.7% of ulcerating and polypoid form with invasive characteristics, and 18.83% of linitis plastica. The pyloric area localisation is the most frequent, 68% of cases. Diffuse tumors are observed in 8.47% of cases and numerous stomach localisation in 0.82% of cases. 84% of histological aspect are represented by adenocarcinoma, the most frequent of them (35%) is well differentiated type, then the poorly differentiated (20%) and atypic form (19.75%). Frequency of lymphosarcoma reaches 14.7%, the first is the centroblastic form, then lymphoblastic and lymphoplasmocytic forms. Concerning evolution, gastric cancer is an infiltrative tumor: serosal surface is attempted in 69.5% of cases, and during the first chirurgical act half cases show lymph nodes metastasis.

Adenocarcinoma↗

[2 cases of mycotic infection caused by Cryptococcus neoformans].

The authors present two cases of Cryptococcus neoformans disease in two young persons. Its appears, in the first case, a diffuse ganglionnary and cutaneous lesion with an evolutive meningo-encephalic localization, and in the second case it appears only a meningitic lesion. These two observations are characterized by the apparition of the infection in a immunodepression patient and by an unfavorable evolution in spite of the treatment.

Adolescent↗

[Anatomo-clinical study of 102 cases of primary lung cancer].

The authors do a clinical anatomic study showing 102 cases of lung primitives cancers to be diagnose in 60% cases on biopsy and 40% on operation'piece. The matter in boundless majority of cases is carcinoma 92%, themselves overlooked by squamous cells carcinoma 55%, forwarded by adenocarcinoma 20%, small cells carcinoma represent 11% of cases and large cells carcinoma 7%. The mean age of occur is 55 years and any cases of carcinoma is observed at persons under 30 years of age. 94% of person are masculine. The majority of tumors 58% cases present themselves as bulky masses exceeding 6 cm of diameter. The authors insist in this study on necessity of early diagnosis when the therapeutic will be curative.

Adenocarcinoma↗

[Anatamo-pathological aspects of malignant ovarian tumors in children. Apropos of 16 cases].

The authors present 16 cases of malignant ovarian tumors in childhood, censed in Pasteur Institute - Tunis. These tumors are scarce, and present in the literature only 3% of the malignant tumors in childhood. In this series, germ cell tumors are the most frequent and present 81.25% of these cases, of which 43.75% of dysgerminoma. Gonadal stromal tumors are more scarce (6.25%). The prognosis of these tumors was transformed by the radiation therapy in dysgerminoma, and the chemotherapy in the other germ cell tumors. These tumors must be diagnosed and treated early.

Adolescent↗

[Bronchial cytology in the diagnosis of broncho-pulmonary cancer in Tunisia].

The authors present a retrospective study of 287 pulmonary cytologic exams censed in Pasteur Institute - Tunis between 1970 and 1986. These 287 exams consist of 145 bronchic aspiration liquids and 142 spittles. A systematic exam was practiced in patients presenting a pulmonary symptomatology suggesting little or not at all broncho pulmonary cancer. 40 of these exams present cancerous cells (15 cases) or suspected cancerous cells (25 cases). The biopsy confirms a malignant tumor in 25 patients (5%). These results should urge us toward a cytologic exam not only in adults presenting any respiratory symptomatology, but also in subjects at high risk, especially smokers. Localising the tumor is necessary for the biopsy. This biopsy will lead us to determine the histologic type and consequently the adequate therapy.

Adult↗