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Biomedical subjects

S N Enikolopov

Publications and source records attributed to S N Enikolopov.

7 recordsLinked to original sources

[The possibilities of adaptation of patients with multiple sclerosis: the results of clinical and psychological study].

A complex clinical and psychological examination of three groups of patients with stable neurological deficit (113 subjects, 77 men and 76 women, aged from 19 to 67 years) included those with multiple sclerosis (MS), chronic cerebral vascular disorders and chronic dorsopathy with illness duration 5-7 years has been carried out. Neuropsychological status and quality of life were assessed using the following tests: Medical Outcomes Study Short Form 36 Health Survey (SF-36); the method of E.B. Fantalova "Level of Ratio of "Values" to "Availability" in Different Life Spheres", Integrative Anxiety Test, Manual for the Constructive Thinking Inventory, Coping test (Lazarus), Beck depression scale. In total, 42 traits on 6 tests have been studied. The study was conducted before and after treatment (21 +/- 2 days). The results revealed that patients with chronic neurological disorders, in particular with MS, often had subclinical depression, which negatively influenced the disease course, and needed treatment. A high level of anxiety was found in MS patients that was related to situational social defensive reaction. Low ability to positive reevaluation of life situations, one of the causes of anxiety states, was observed in all the groups, especially in MS. In MS patients, their real state was not consistent with their perception of this state. They also were featured by personal superstitious thinking. Most of the patients with MS had a good constructive thinking, preserved ability to emotional and behavioral self-control that indicated favorable prognosis in future complex rehabilitation. After the course of symptomatic vascular and metabolic therapy, with the exception of antidepressants and neuroleptics, the appearances of depression and anxiety as well as expression of social defensive reactions and situational phobic component of anxiety were decreased that suggested the necessity of inclusion of individual psychotherapy as a part the complex rehabilitation therapy.

Adaptation, Psychological↗

[Use of cluster analysis for the study of self-stigmatization phenomenon].

Cluster analysis was used in the study of self-stigmatization phenomenon measured with the original self-stigmatization questionnaire in 81 patients with schizophrenia, affective and neurotic disorders. The answers presented by digital codes were analyzed statistically. Six factors of self-stigmatization were as follows: "a victim of stigma", "deidentification from the healthy", "predisposition to identification with mentally ill", "avoidance of mentally ill", "excuse by mental illness" and "generalization of stigma".

Adult↗

[Complex evaluation of neuropsychological cognitive and emotional personality disorders in multiple sclerosis].

UNLABELLED: 30 patients with definite MS and mild or moderate disability were tested with expended neuropsychological, psychiatric, psychological, neurological, neurophysiological, MRI methods. The aim of the study was to analyse the role of cognitive, emotional and personal peculiarities in MS clinical picture and its influence on patients adaptation and quality of life. It was found, that patients with MS had high level of personal anxiety, emotional ways of coping and low scores in constructive reasoning, narrowing of motivation sphere. Neuropsychological test performance revealed low level in activation, regulatory and operation brain processing connected with dysfunction in relations of profound structures with frontal brain and dysfunction of temporal-occipital zones of right hemisphere and also with connections between hemispheres. CONCLUSION: All changes had relationship with brain MRI abnormalities and neurophysiological characteristics.

Adult↗