Biomedical subjects
Publications and source records attributed to S N Genyk.
Indications for application of lumbar sympathectomy (LS) in chronic arterial insufficiency of the lower extermities are analyzed. The results of the use of lumbar chemical desympathisation under computer tomography (CT) control in 10 patients are represented. Prevalences of chemical desympathisation and LS were revealed which allow us to recommend it for clinical practice.
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Experience in the treatment of 214 patients with diabetic angiopathy complicated by pyonecrotic processes is generalized. Adequate correction of diabetes mellitus, improvement of microcirculation, dietotherapy, and sanitation of the pyonecrotic foci are the main trends in the complex of therapeutic measures. Hemosorption was applied successfully for detoxifixation in 24 patients. Prolonged intraarterial therapy was also conducted with a [symbol: see text] B-1 gent dosing apparatus. Necrosis of the soft tissues and gangrene of the toes or foot were managed by thorough excision of the necrotic tissues and exarticulation or amputation of the toes and metatarsals, and, in exceptional cases, amputation of the limb through the thigh was resorted to. With such complex therapy the number of amputations through the middle and upper third of the thigh was reduced to 18.3%.
Of the 350 patients who died in 1978-1988 from pulmonary thromboembolism (PTE) in 3 clinics of Ivano-Frankovsk, the surgical patients accounted for 36% (51.6% of them--at the age of 60 years and older). The likelihood of the PTE development is the highest during the first week after the operation performed, as a rule, for a malignant tumour of the alimentary organs, vascular diseases, and after prostatectomy.
The experience with treatment of 214 patients suffering from diabetic angiopathy complicated by purulent-necrotic tissue lesion, which included intraarterial administration of antibiotics, insulin, novocaine, vasodilators, antiaggregants, anticoagulants, vitamins, is summarized. In soft tissue necrosis, gangrene of the toes, or foot, the necrotized tissues were excised, exarticulation, or amputation of toes, metatarsals, in extreme cases, amputation of a leg at the thigh level, were performed.
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A 20-years experience of the clinic with substantiation of the surgeon's tactics for acute thrombophlebitis of superficial veins of lower extremities is presented. A conclusion is made that radical operations for acute thrombophlebitis of superficial veins of lower extremities without special preoperative preparation prevent further spread of the thrombotic process, development of thromboembolism of the pulmonary artery, make the duration of treatment at the hospital 2 times shorter and contributes to quicker recovery of working ability.
The article discusses the in- and out-patient modalities of maintenance of health of patients with uncomplicated varicosity of the lower limbs in rural areas. The authors point to the advantage of this modality of treatment and formulate the recommendations for carrying out measures which ensure successful treatment of this category of patients. The criteria of effective treatment are a shorter period of in-patient treatment due to preoperative out-patient examination and postoperative out-patient treatment, the absence of recurrences of the disease, and the patient's return to occupational activity.
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In the experiment on dogs, the authors modelled acute ischemia of the extremities and studied the activity of lactate dehydrogenase in the blood serum. In circulatory ischemia for 2 and 4 h, the metabolism in muscular tissue normalized by day 30 after restoration of blood flow. Circulatory hypoxia for 7 and 9 h led to failure of the compensatory-adaptive mechanisms of homeostasis of the muscular tissue and required performance of regional detoxication therapy before restoration of circulation in the extremity.