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Biomedical subjects

S N Martyak

Publications and source records attributed to S N Martyak.

9 recordsLinked to original sources
PubMed1985

Fibrous mass complicating epidural morphine infusion.

The benefits of continuous epidural morphine infusion using an implanted pump delivery system to control intractable cancer pain have recently been described. Most articles on this subject relate to dosage, technique, degree of pain relief, and tolerance. There are some anticipated complications of the treatment related to the surgical implantation of the system and drug toxicity. We present a complication presumably related to the epidural catheter. A fibrous reaction that developed around the catheter tip progressed into a mass. This caused a significant displacement of the spinal cord with the development of long tract symptoms. Identification of this abnormality using myelography and computed tomography led to prompt surgical decompression resulting in improvement of the patient's condition.

Aged↗
PubMed1977

Risk factors and early diagnosis in pancreatic carcinoma.

A case is reported of pancreatic carcinoma recognized four years after bile peritonitis complicated cholecystectomy. The patient possessed all the known significant risk factors associated with pancreatic carcinoma. The wider recognition of risk factors for pancreatic adenocarcinoma might lead to closer follow-up of patients with multiple factors and possible earlier diagnosis and treatment leading to increased survival in patients with the disease.

Adenocarcinoma↗
PubMed1976

Abdominal incision and closure. A systems approach.

The application of systems analysis and flow charting technics to abdominal incision and closure allow a complete display of objectives and alternatives. A route of alternatives has been chosen and supported by the best available principles in the surgical literature. The choices include an unconventional large bite monofilament continuous one-layer closure of the abdominal aponeurosis as well as several less commonly used principles to minimize the risk of wound infection. The process of graphic display of objectives and alternatives in a surgical procedure or disorder allows one to more sharply focus on alternatives at different steps and more rigidly support them by careful analysis of past experience or review of the literature.

Abdomen↗
PubMed1976

Penetration of clindamycin phosphate into the abnormal human biliary tract.

Clindamycin phosphate, 600 mg, was given intravenously to 14 patients undergoing biliary tract surgery. Seven had complete obstruction of the common bile duct. Concentrations of total and active (nonesterified) antibiotic were measured in serum, gall bladder and common duct bile, gall bladder wall, and liver. Persons with patent common ducts had high levels of active drug at all hepatobiliary sites; concentrations were two and one half to three times higher in bile and liver than in serum. Persons with obstruction of the common duct had no measurable drug in bile and had reduced levels in gall bladder wall; however, concentrations in the liver were slightly higher than those in the group without obstruction. The results of this study suggest that, even in the presence of common duct obstruction, the concentrations of active clindamycin in the liver may be sufficient to limit the spread of intrahepatic infections due to susceptible organisms.

Anti-Bacterial Agents↗