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Biomedical subjects

S N Tripathy

Publications and source records attributed to S N Tripathy.

12 recordsLinked to original sources
PubMed2003

Tuberculosis and pregnancy.

OBJECTIVES: There are many myths surrounding pregnancy and tuberculosis (TB), and outcome of treatment. This prospective study was conducted at the Department of Obstetrics and Gynecology, SCB Medical College, Cuttack, India, and at the authors' private clinics from 1986 to 2001 to determine the outcome of pregnancy if TB is treated properly. METHODS: A total of 111 pregnant women diagnosed as having pulmonary and glandular TB were included in the study. They were matched for age, parity, and socioeconomic status with 51 pregnant women without TB (first control group), and 51 women with pulmonary TB but without pregnancy (second control group). The usual pregnancy management was given to the women in the study group, along with a short course of chemotherapy: either ethambutol, INH, or rifampicin and pyrazinamide for 2 months followed by INH and rifampicin for 4 months; or ethambutol, INH, and rifampicin for 2 months followed by INH and rifampicin for 7 months. Statistical analysis was done using a chi(2)-test. RESULTS: There were no statistical differences in duration of gestation, preterm labor, and other complications of pregnancy, labor, and puerperium between the pregnancy groups. There were no congenital anomalies in the babies born to the groups. Pregnancy had no effect on the course of TB as regards sputum conversion, stabilization of the disease, and non-relapse even after 2-5 years of follow-up and a further delivery in a few cases. CONCLUSIONS: If proper and adequate chemotherapy is given to pregnant women with TB, they are not a higher risk than non-pregnant women with TB. Neither the disease nor chemotherapy is threatening to mother or newborn. However, today the ominous combination of human immunodeficiency virus, TB, and pregnancy poses a new challenge.

Adult↗
PubMed2003

Tuberculosis and general practitioners.

In spite of advancement of knowledge in diagnosis and management, tuberculosis is still the biggest health problem. There are more than 400 million people infected with tuberculous bacillus and more than 14 million cases are suffering from the disease. Prevention, control and care of tuberculosis are possible. General practitioners play a major role in combating the disease. Quick and right diagnosis and treating the cases effectively should be the motto. Sputum microscopy is the backbone of diagnosis of tuberculosis. With the availability of modern chemotherapy the outcome of a tuberculosis case has undergone dramatic changes. Short-course chemotherapy is the standard choice while tackling cases of tuberculosis. Results of directly observed treatment (DOT) strategy are very good provided execution is proper. HIV/AIDS, another dreaded disease if becomes co-infected along with tuberculosis, mortality and morbidity become very high. The general practitioners are the major strength of healthcare system in any society. They should be good enough to know all about the control programmes well implemented in the country.

Antitubercular Agents↗
PubMed2002

Physical status of newborns and neonatal outcome.

OBJECTIVE: To determine the extent to which physical status at birth is associated with neonatal mortality and the causes of mortality vis-a-vis size at birth and gestational age. METHOD: 11,223 consecutive live births completing 26 weeks of gestation and weighing > or = 500 gm were included in the study. Birth weight and chest circumference were recorded as per WHO guidelines. Gestational age was calculated on the basis of L.M.P. and the new Ballard's score. Deaths occurring in the hospital within 28 days were recorded. Percentile values of gestational age specific birth weights were calculated separately for singletons and multiple births. Percentage of SGA was calculated with reference to WHO recommended values. Birth weight-gestational age-specific mortality rates were calculated at 2 wk and 500 gm intervals. RESULT: Low-birth-weight babies constituted 39.8% of the total, much in excess of WHO recommended figure of 15%. 76% deaths occurred among LBW babies and 56.2% among preterms. Mortality showed remarkable decline as the birth weight increased to 2,000 gm. The lowest mortality was among singletons weighing 2,500-3,000 gm and of 38-40 weeks gestation. Prevalence of SGA at 40 and 42 weeks were 73.7% and 83.6% respectively. But, if SGA babies not categorised as LBW were excluded, the values came down to 32% and 36% respectively. 36% of all deaths occurred during the first 24 hrs of birth; asphyxia and related causes contributing to 50% of it. CONCLUSION: Cut-off value of 2,000 gm instead of 2,500 gm for birth weight may be preferable in countries where most LBW babies are SGAs. Simultaneously, deaths in non-LBW babies due to perinatal causes contribute sgnificantly to total neonatal mortality and need due attention through sensitising obstetricians in essential newbom care and timely Intervention.

Birth Weight↗
PubMed1990

Laparoscopic observations of pelvic organs in pulmonary tuberculosis.

Sixty-two cases of bacteriologically positive pulmonary tuberculosis were studied in the Department of Tuberculosis and Chest Diseases at the V.S.S. Medical College Hospital, Burla, India. Apart from other investigations, all patients underwent laparoscopy to determine the incidence of genital involvement. Positive findings were observed in 37 women; tubercles were present in the tubes of 15 women. At dilatation and curettage, the endometrium was obtained in 37 women. Tuberculous endometritis was detected in 4 women.

Adolescent↗
PubMed1990

Place of aspiration cytology in dysfunctional uterine bleeding.

In 150 cases of dysfunctional uterine bleeding the endometrial aspiration cytology was compared with histopathology in order to know the value of the former in such cases as the technique is found to be safe, simple, reliable and well accepted by patients as an outpatient department procedure. The material was adequate in 93% cases for cytology. It tallied 100% in tuberculosis and 94% in rest of the diseases with histopathology. Both the methods were equally effective in diagnosing and phasing the endometrium. But it becomes mandatory to follow up the cases where a malignant smear is not corroborated by histopathology.

Adult↗
PubMed1981

Genital manifestation of pulmonary tuberculosis.

We studied 200 women with pulmonary tuberculosis to check for genital lesions: 13% of these women had genital tuberculosis. As clinical diagnosis was not possible, we relied on meticulous and repeated histopathologic studies. The occurrence of genital tuberculosis was more frequent in women who had pulmonary tuberculosis of shorter duration, but was not related to the severity of the disease. Pulmonary tuberculosis indirectly affects the female genital tract in almost all cases, giving rise to various gynecologic symptoms and signs. A review of the literature and further discussion about this subject are presented.

Adolescent↗