Macromolecular complexes of drugs. I. Doxorubicin-heparin complex.
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Biomedical subjects
Publications and source records attributed to S Nagamitsu.
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Intrahepatic pigment calculi are frequently found in East Asia and are associated with a considerable morbidity and mortality. The various methods of surgical treatment are unsatisfactory. A wraparound end-to-end hepaticojejunostomy presented may provide an effective and alternative method of treatment.
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A case of fibrosarcoma arising in the scar of the radical mastectomy with postoperative irradiation of breast carcinoma is reported. The tumors arose five times in spite of the extirpations including surrounding tissue since 11 years after radical mastectomy and postoperative irradiation. All of arisen tumors were diagnosed fibrosarcoma histologically and with every recurrence the aggravation of malignancy of tumors was shown. In this case, the primary tumor of the breast was infiltrating carcinoma and no sign of fibrosarcoma was noted histologically. The mastectomy scar was indicated the irradiation therapy postoperatively and fibrosarcoma developed 11 years after postoperative irradiation. Namely, this case agreed to the strict criteria of the postirradiation sarcoma proposed by Cahan et al. In this paper, a case of postirradiation fibrosarcoma arising in the scar of radical mastectomy for carcinoma is presented.
So-called authors' lithogenic bile [Ch greater than 7.5 mg/ml, (TBS + PL)/Ch weight ratio less than 20] corresponds to the bile which falls well above the micellar zone boundary on triangular coordinates with high concentration of cholesterol. The authors supposed that, in man like hamsters and squirrel monkeys, in the process of alimentary formation of cholesterol gallstones gallbladder bile of which cholesterol concentration was high, and (TBS + PL)/Ch ratio was as low as that of gallbladder bile with cholestrol gallstones seemed to be lithogenic.
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