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Biomedical subjects

S Negreira Cepeda

Publications and source records attributed to S Negreira Cepeda.

9 recordsLinked to original sources

[Chronic multifocal osteomyelitis].

The cases of three female Guinean children are described. Bloods tests were nonspecific, showing a moderately high globular sedimentation rate. The patients received combined therapy with systemic antibiotic therapy (including local gentamicin administration in two of the three patients) and surgery. One patient returned to Guinea and was lost to follow-up. The second patient showed severe sequelae and the third patient had a favorable outcome. In recent years, the prevalence of chronic osteomyelitis in Africa has increased. Most patients have multiple bone involvement and multiple etiology. Blood cultures are negative in 40 % of patients and severe radiologic abnormalities, most commonly fractures, are frequent. A successful therapeutic regimen must be based on antibiotic and surgical treatment.

Child↗

[Clinical profile, course and outcome of gastroesophageal reflux in 10 infants under active medical treatment].

We have studied the clinical profile, cause and outcome of 105 infants with the diagnosis of gastroesophageal reflux. In most cases, pharmacological treatment managed to control the symptoms in 9 out of 10 infants followed in our series. Complications were described in 26.2%, of which esophagitis and chronic respiratory disease were the most common. Corrective surgery of the reflux was indicated in those cases in which pharmacological treatment was not successful. This managed to control the reflux in 90% of all cases. Morbidity was scarce. In all, 75% of the infants were considered to be medically cured within 15.5 months from the time that they were diagnosed and within 18.5 months after the appearance of the first symptoms.

Esophagitis, Peptic↗

[Analysis of a recent laryngitis outbreak].

In the present paper the incidence and severity of croup during the months of september, october and november of the last three years is analyzed. The existence of an important outbreak of laryngitis in the autumn of 1987, with a peak of incidence during the month of october is shown. A prospective study about the children with croup admitted in a pediatric center during the epidemic period in 1987. Was done after serologic and cell-virus culture tests it became clear that the parainfluenza virus type 1 was the cause of the outbreak, as excepted. We suggest the possibility of another laryngitis outbreak in 1989 if there is not change in the epidemiologic pattern of the virus.

Humans↗

[Determination of heterophilic antibodies in infants: apropos of nine cases].

The most frequent and known disease produced by Epstein-Barr virus is infectious mononucleosis. It is usually diagnosed after the age of two in pediatric practice based on the characteristic hematologic picture and Paul-Bunnell test. In infants there is rarely communications of this cases in the literature and, moreover, Paul-Bunnell test is commonly negative. We have collected nine infants below two years old with mononucleosis syndrome characteristic hematologic picture and with heterophil antibodies positive reaction in all of them. Clinical and laboratory finding, and it likely relation to the EBV infection are discussed.

Antibodies, Heterophile↗

[AIDS-related disease in an infant. A new entity to consider in pediatrics].

Recently some cases of AIDS and AIDS-related disorders in children have been published. Some of them had received blood transfusions, others were secondary to AIDS in the mother (vertical transmission). Authors report a case of an 18-month old male infant who became seriously ill when he was 13-month old, and which proved particularly difficult to diagnose until specific serology for HTLV-III, was performed at the age of 16 months. Authors believe that due to growing incidence of AIDS and AIDS-related diseases it is essential to dismiss this diagnosis in infants with a history of transfusion, maternal transfusions or family drug abuse or promiscuity.

Acquired Immunodeficiency Syndrome↗