[Cholera today].
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Biomedical subjects
Publications and source records attributed to S Neumann.
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46 patients underwent synovectomy of the cubital joint for rheumatoid arthritis during the last seven years (1970 to 1977). 38 patients were followed up. The articular function improved in 71%, pain had been eliminated in 55%, no effusion was any longer present in 71%. In advanced stages of the disease resection of the head of the radius generally is performed because it facilitates surgery and improves the articular function later on. Synovectomy is recommended at an early stage.
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The activity of enzymes involved in glycolysis, gluconeogenesis, and lipoenesis in early and term human placenta was determined. A high activity of pyruvate kinase was found, indicating high glycolytic potential. The activity of this enzyme tended to decrease with gestation. The presence of phosphoenolpyruvate carboxylase activity was detected, suggesting the possibility of gluconeogenesis in the placenta. Very low activity of enzymes involved in fatty acid synthesis was found, whereas the activity of the pentose shunt pathway enzymes, glucose-6-phosphogluconate dehydrogenases, was relatively high. This suggested a role of this pathway in the synthesis of lipids other than fatty acids in the placenta. The activities of enzymes in the human placenta and their changes during gestation where compared to previous observations on enzymes in rat placenta.
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