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S Ngadiman

Publications and source records attributed to S Ngadiman.

9 recordsLinked to original sources
PubMed1997

Malignant struma ovarii. A case report and review of the literature.

Malignant struma ovarii is a rare form of ovarian carcinoma; only 3 cases of its pure papillary type have been reported in the literature. A new case of malignant papillary struma ovarii arising in an asymptomatic 32-year-old woman is presented. Due to its rarity, there has been confusion in the diagnosis and management of malignant struma ovarii. Criteria for the diagnosis of malignant papillary struma ovarii are proposed. Conservative treatment after a complete staging procedure is possible due to the usually benign course and low incidence of metastases of this tumor.

Adult↗
PubMed1997

Intraluminal crystalloids in breast carcinoma. Immunohistochemical, ultrastructural, and energy-dispersive x-ray element analysis in four cases.

OBJECTIVE: Intraluminal crystalloids have been described in the prostate, salivary gland, and ovary, but have not yet been reported in the breast. We report four cases of breast carcinoma in which these crystalloids were found in ducts with intraductal carcinoma or atypical hyperplasia. The presence of intraluminal crystalloids may be a useful adjunct in making a diagnosis of carcinoma or may be a feature to look for as a marker for the presence of carcinoma. DESIGN: Four cases of breast carcinoma containing intraluminal crystalloids were identified among 6900 surgical breast specimens between January 1990 and June 1995 at M. D. Anderson Cancer Center, Houston, Tex. Those sections with crystalloids identified by hematoxylin-eosin stain were stained with periodic acid-Schiff, Alcian blue, and mucicarmine stains. Immunohistochemical and ultrastructural studies and energy-dispersive x-ray analysis were also performed on these sections. RESULTS: The intraluminal crystalloids were eosinophilic, varied in shape and size, and did not exhibit birefringence under polarized light. Immunohistochemically, the crystalloids were negative for keratin, muscle-specific actin, and kappa and lambda light chains, but the surfaces stained positively for epithelial membrane antigen. By electron microscopy, the crystalloids had no limiting membrane and were composed of an electron-dense material with no discernible periodicity. By energy-dispersive x-ray element analysis, the crystalloids had no mineral content; however, sulfur was found, indicating a protein content. CONCLUSIONS: The pathogenesis and constituents of these intraluminal crystalloids remain to be determined. Inasmuch as intraluminal crystalloids have not been found in normal ducts or acini, or in ductal hyperplasia without atypia, their presence may serve as a marker for breast carcinoma.

Adult↗
PubMed1994

The concurrence of duodenal epithelioid stromal sarcoma, pulmonary chondromatous hamartoma, and nonfunctioning pancreatic islet cell tumor. A possible analogue of Carney's triad?

A 63-year-old man with non-insulin-dependent diabetes mellitus and peripheral vascular disease presented with acute pulmonary edema and ascites. He died after a brief illness. Coincidence of duodenal epithelioid stromal sarcoma, pulmonary chondromatous hamartoma, and pancreatic islet cell tumor was found at autopsy. This rare concurrence of three uncommon neoplasms may be a pathogenetic variant or an analogue of Carney's triad in an elderly individual. Since all three tumors expressed markers for neural differentiation, the coincidence of tumors with these features may represent a form of neurocristopathy.

Adenoma, Islet Cell↗
PubMedDate not supplied

Adenomyomatous, lower uterine segment and endocervical polyps in cervicovaginal smears.

To the best of our knowledge, the specific features of polyps in cervicovaginal smears have not been described; that fact prompted us to undertake this study. Fifty-seven cases of polyps below the uterine fundus with cytohistopathologic correlations were analyzed. The tissue diagnoses were 2 cases of adenomyomatous, 2 cases of lower uterine and 53 cases of endocervical polyps. In the cervicovaginal smears, adenomyomatous polyps presented as cohesive fragments with frayed edges, revealing spindle cells with bipolar cytoplasmic processes. Lower uterine segment polyps showed peculiar tissue fragments composed of several fractured arterioles connected by sheets of small stromal cells. Endocervical polyps presented as smooth-bordered, polypoid tissue fragments, lined at the outermost layer with simple columnar cells, sandwiched within a pale intermediate zone and packed at their inner core with numerous small, dark stromal cells. This specific finding, however, was observed in only one case. The remaining 52 patients had no specific findings in their smears.

Adenomyoma↗
PubMedDate not supplied

Infantile myofibromatosis with hemangiopericytoma-like features of the tongue: a case study including ultrastructure.

We report a case of an infantile myofibromatosis with hemangiopericytoma-like features arising in the tongue of a 5-month-old female infant. Many authors now classify neoplasms as infantile myofibromatosis that were previously called infantile hemangiopericytoma. The ultrastructural features of our tumor illustrate its biphasic nature and provide a possible explanation for its histogenesis. Infantile myofibromatosis, including those diagnosed as infantile hemangiopericytomas, rarely arise in any intraoral location. Despite the generally good prognosis associated with these neoplasms, complete surgical excision is recommended to avoid recurrences.

Diagnosis, Differential↗