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PubMed1977

Lymphocytic infiltration in long-survival glioblastomas: possible host's resistance.

A series of 200 patients operated on at the Rome University Neurosurgical Clinic for primary glioblastoma is analyzed. Eight of these patients (4%) survived for over four years. The histological preparations showed more or less heavy perivascular lymphocytic infiltration in six of these cases. Since such infiltrations in malignant tumours of other organs are recognized as having an immune function, expressing the host's resistance to his tumour, the longer survival of the cases considered may well denote an immune defensive mechanism.

Adolescent↗

PubMedDate not supplied

[Primary intraorbital meningiomas].

The authors found in literature the description of 124 cases of intra-orbital primitive meningiomas; they illustrate their clinico-surgical aspects as well as the differential features on the ground of their point of origin: 90 meningiomas of the (dural) sheath of the optic nerve (23 intraforaminal ones and 67 extraforaminal ones), 34 extradural meningiomas; they present 4 original cases, 3 extradural ones and 1 of the sheath of the optic nerve. After describing the elements of differential diagnosis with the most common intra-orbital expansive lesions (gliomas, sarcomas, angiomas, psuedotumors or orbital granulomas) the authors end by stating that total extirpation must be always carried out including, if necessary, the optic nerve and the ocular globe when it is invaded.

Adult↗