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S Nose

Publications and source records attributed to S Nose.

26 records · Page 2Linked to original sources
PubMed1990

[A case of two primary carcinomas: thyroid papillary carcinoma with anaplastic transformation of metastatic cervical lymph node and breast cancer].

Reported is the case of a 70-year-old woman who, on diagnosis, was found to have a papillary carcinoma of the thyroid gland that showed an anaplastic transformation of a metastatic lesion of the right cervical lymph node. The primary lesion, however, contained no anaplastic areas. Simultaneously, she also was found to have a primary carcinoma of the left breast, an invasive ductal carcinoma. She thus received a total thyroidectomy with a right cervical node dissection, a modified radical mastectomy, and irradiation of the right cervical area, but no intensive chemotherapy was performed. Six months after the thyroidectomy, the anaplastic carcinoma caused her death. On autopsy, it was found to have involved the right cervical area, the lungs, the mediastinum, the right axilla, and the right kidney.

Aged↗
PubMed1990

[An operative case of benign schwannoma originating in the intrathoracic vagal nerve].

A 50-years-old man was admitted with cough and abnormal shadow on the chest film. The tumor originated from the left vagal nerve in the antero-superior mediastinum. Subcapsular extirpation was performed to save the nerve function, since the tumor located in the site proximal to the branching point of the recurrence nerve. Pathological diagnosis was a benign schwannoma. Though H-E and Bodian stain did not show any nerve fibers in the schwannoma, postoperative hoarseness arose. In this country, 4 cases of subcapsular extirpation have been performed, but all of them had postoperative hoarseness. We think that postoperative hoarseness cannot be prevented by the subcapsular extirpation.

Cranial Nerve Neoplasms↗
PubMed1989

Ontogeny of S-100 protein-positive histiocytes and lymphocytes in the human fetal lymphoreticular system.

In the human lymphoreticular system, the alpha and beta subunits of S-100 protein are found in ordinary monocyte-macrophages and non-phagocytic histiocytes such as Langerhans cells and interdigitating reticulum cells, respectively. The beta subunit is also present in some CD8+ T cells. In the present study, we investigated the ontogeny of these histiocytes and lymphocytes in humans. Yolk sacs and 4 to 21-week fetuses were examined immunohistochemically for the presence of S-100 protein subunits using antisera monospecific to each subunit. S-100 alpha + macrophages were present in the yolk sacs and the hepatic sinusoids of the 4th week embryos prior to bone marrow hematopoiesis. These macrophages later appeared in other lymphoid organs when anlagen of these organs were formed. No S-100 beta + cells were found in the yolk sacs. S-100 beta+ histiocytes were first detected in the hepatic sinusoids of the 5th week embryo, and after the 8th week of gestation, they were distributed in other lymphoid organs. S-100 beta+ lymphocytes were not found in the liver. They were first detected in the thymus at the 12th week of gestation, and were subsequently distributed in other lymphoid organs. These results suggest that S-100 beta+ lymphocytes and histiocytes may belong to different cell lineages, and the former may not be the precursor of the latter.

Gestational Age↗
PubMed1987

An immunohistochemical study on the distribution of glial fibrillary acidic protein, S-100 protein, neuron-specific enolase, and neurofilament in medulloblastomas.

In order to clarify the differentiation of medulloblastomas, the authors studied on the morphological features and immunohistochemical expression of glial fibrillary acidic protein (GFAP), S-100 protein, neuron-specific enolase (NSE), and neurofilament (NF) in 31 medulloblastomas. GFAP was detected only in a small number of tumor cells of 5 medulloblastomas; S-100 protein in both small tumor cells and some so-called spongioblastic cells in 16 medulloblastomas; NSE in the more abundant tumor cells and the matrix in 28 medulloblastomas; NF in a few tumor cells of 12 medulloblastomas; GFAP and NF in 2 medulloblastomas, but each of them in different tumor cells. These results suggest that medulloblastomas have a capacity of differentiation along neuronal and/or glial lines. The conventional morphological markers of differentiation in medulloblastomas such as spongioblastic cells and Homer Wright rosettes were not necessarily compatible with expression of immunohistochemical markers such as GFAP or NF. NSE and S-100 protein seem less valuable markers of differentiation because they were detected in both neuronal and glial elements. But NSE, which was observed in most medulloblastomas, might have a value as a marker for medulloblastomas.

Adolescent↗
PubMed1985

Immunohistochemical studies on human brain tumors using anti-Leu 7 monoclonal antibody in paraffin-embedded specimens.

Using the four-step peroxidase-antiperoxidase (PAP) method, the presence of the antigen recognized with anti-Leu 7 monoclonal antibody was investigated in paraffin-embedded human brain tissue and tumors. The antigen was demonstrated in the myelin sheaths, oligodendrocytes, and some choroid plexus cells in normal brain and in oligodendrogliomas, some astrocytomas and choroid plexus papillomas. The technique can be used to identify normal and neoplastic oligodendrocytes.

Antibodies, Monoclonal↗