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Biomedical subjects

S Novi

Publications and source records attributed to S Novi.

17 recordsLinked to original sources
PubMed1999

Effect of clofibrate, a peroxisome proliferator, in sea bass (Dicentrarchus labrax), a marine fish.

The effects of 35 or 70 mg/kg clofibrate on some peroxisomal, mitochondrial, and microsomal enzymes (markers of peroxisome proliferation) in liver, gill, and kidney of sea bass following 2 weeks i.p. treatment have been studied. Induction of lauric acid hydroxylase, UDP-glucuronyl transferase, palmitoyl-CoA oxidase, carnitine-palmitoyl-transferase, p-nitrophenylacetate hydrolase, and benzaldehyde and propionaldehyde dehydrogenase activities was not observed in any case. The clofibrate administration at the dose of 70 mg/kg induced in the liver the glutathione S-tranferase and reduced epoxide hydrolase activities. These results demonstrate that a marine fish species, such as sea bass, is refractory to peroxisome proliferation.

Animals↗
PubMedDate not supplied

[Evaluation of a prevention and prophylaxis program for the handicapped].

The growing interest regarding the importance of oral health in subjects affected with physical and psychological handicaps has led the Authors to prepare a programme of oral hygiene aiming at the prevention of dental and periodontal diseases and demanding the participation of the other members of the families, the educators and the specialized staff put at the head of their assistance. Fifty-three subjects presenting different pathologies, who have undergone elementary operations of oral hygiene, have been examined. In order to value the efficacy of these systems, DI (Debris Index), CI (Calculus Index) and OHI (Oral Hygiene Index) of Greene and Vermillion have been periodically calculated. The results obtained have been encouraging and have emphasized the importance of the behaviour of family and institutions towards people with physical and psychological handicaps, in order to let a project of primary prevention succeed.

Adolescent↗