Biomedical subjects

S Nyulassy

Publications and source records attributed to S Nyulassy.

At least 37 records · Page 2Linked to original sources

PubMed1988

The importance of immunohistochemical examination of glomerulonephritis.

There were 942 cases of glomerulonephritis classified according to WHO out of 1499 renal biopsies. Immunoglobulins IgG, IgA, IgM, C3 and fibrinogen were examined immunohistochemically in a standard way and IgD, IgE, albumin, C4 and HBsAg in a non-standard way. The results were compared with a control group. The results show that the excluding value of the negative immunohistochemical examination in glomerulonephritis is higher than the proving value of the positive examination.

Complement C3↗

PubMed1988

HLA-DP antigens provide the proliferative impetus for the generation of cytotoxic T lymphocytes.

Investigating HLA-A, -B, -C, -DR and -Dw antigens and MLR, CML, and PLT reactivity in two unrelated persons, it was found that, despite their HLA-D/DR identity, cytotoxic T lymphocytes (CTL) could be induced in the CML assay. The HLA-DP antigens proved to provide the proliferative impetus for the generation of CTL.

Cell Division↗

PubMed1985

Plasma cells in aspirates of goitre and overt permanent hypothyroidism following subacute thyroiditis. Preliminary report.

The occurrence of permanent overt hypothyroidism (POH) following subacute thyroiditis (SAT) was studied in 103 patients during 11-142 months (mean 52.8 months). Increased amount of plasma cells in cytological pictures of goitre aspirates was found at the time of diagnosis of SAT in 25 cases (24.3%). POH developed in 11 patients (10.7%). Eight patients with high titres of circulating thyroid antibodies demonstrated also cytological characteristics of autoimmune thyroiditis (increased amount of plasma cells inclusively) at the time of the diagnosis of SAT. Early developing POH in these patients was found. The association with HLA-Bw35 in this subgroup was not striking. In another subgroup of 3 patients POH developed after an interval of several years of euthyroidism following SAT. In such cases the autoimmune thyroiditis was not conspicuous and HLA-Bw35 was found in all 3 cases. Increased amount of plasma cells in aspirates of goitre at the time of symptomatology of SAT was observed only in one patient. It is concluded that increased amount of plasma cells (in addition to usual cytological picture of SAT) in aspirates of goitre at the time of clinical manifestation of SAT may be a warning of increased risk of development of permanent hypothyroidism following SAT. Some speculations on possible heterogeneity of subacute thyroiditis are presented.

Acute Disease↗

PubMed1984