[Effects of antioxidants on content of bioelements in the blood of newborn infants after chronic intrauterine hypoxia].
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Biomedical subjects
Publications and source records attributed to S O Kliuchnikov.
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Emission analysis with the use of induced plasma was employed to measure the content of 9 bioelements (potassium, sodium, calcium, magnesium, phosphorus, iron, copper, zinc and selenium) in the blood serum of 82 neonates with a history of chronic intrauterine hypoxia and in 19 normal children at birth and in the course of early adaptation. It has been shown that the content of bioelements in the blood of normal neonates was marked by a number of characteristic features reflecting to a considerable degree the processes of metabolic adaptation of the children to the intrauterine life. The neonates with a history of hypoxia demonstrated the unbalance of bioelements most pronounced by day 3 of life. The treatment instituted did not make the content of bioelements in the neonates' blood return to normal.
The authors describe the results of studying lipid peroxidation, total antioxidant activity of plasma and the content of essential trace elements (iron, copper, zinc and selenium) in 35 healthy neonates and in 32 with intrauterine hypotrophy, grades I-III, at birth and the course of the early neonatal period. It has been found that in the neonates with a history of intrauterine hypotrophy, activation of lipid peroxidation resulted in the decrease of plasma antioxidant activity and in the changes of the concentration of essential trace elements.
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