PubMed Health⌕ Search

Biomedical subjects

S Odagiri

Publications and source records attributed to S Odagiri.

At least 55 records · Page 3Linked to original sources
PubMed1992

[Combined medical and surgical treatment of 74 cases of acute type III aortic dissection].

In the early period up to 1986, our treatment of acute type III dissection was anti-hypertension drug therapy as a rule, and Collins operations were performed in two cases of progressive hemothorax. Among 21 patients receiving medical therapy, five died of rupture, and three operated cases died of multiple organ ischemia, and then the hospital mortality was 40%. Since 1987, we have selected hypotensive treatment of strictly maintaining blood pressure less than 120mmHg for the completely thrombosed type of the dissected lumen, and the emergency operation of ringed intraluminal graft insertion (RIG operation) for the blood-flow type and aneurysm formation type of the dissected lumen, diagnosed by the emergency cine-angiography. As the result, among 51 cases having hypotensive therapy, one died of respiratory failure. In the 23 operated cases, in which RIG operation and/or arterial reconstruction was performed, four died of multiple organ ischemia. The hospital mortality was 8%, which was significantly improved compared with that of the early period.

Acute Disease↗
PubMed1992

[A clinical study on panipenem/betamipron in chronic respiratory tract infections].

Panipenem/betamipron (CS-976, PAPM/BP), a new carbapenem antibiotic, was administered a single dose of 500 mg or 750 mg via intravenous drip infusion twice a day for treatment of chronic respiratory infection to study its clinical efficacy, bacteriological efficacy and safety. Twenty nine cases were studied for the efficacy evaluation. Only the safety evaluation was made in 6 cases which were judged to be unsuitable, because in some of them pneumonia and other diseases were not specified as the subject diseases, of serious illness in some the conditions were too serious, and in the other cases the duration of administration was insufficient since administration had to be discontinued due to side-effects. The duration of administration was 6 to 18 days with 1 g divided into 2 doses daily or 4 to 15 days with 1.5 g in 2 divided doses daily. When clinical efficacies were classified according to different diseases, this preparation was effective in 11 cases and slightly effective in 1 case of 12 cases of chronic bronchitis with an efficacy rate of 91.7%. It was effective in 10 cases, slightly effective in 1 case and ineffective in 1 case of 12 cases of bronchiectasis with an efficacy rate of 83.3%. It was slightly effective in 2 and ineffective in 1 out of 3 cases of diffuse panbronchiolitis, and was effective in 2 cases of pulmonary emphysema with infections. PAPM/BP was given at a dose level of 1 g in 2 divided doses daily to 17 cases and that of 1.5 g in 2 divided doses daily to 10 cases. For the remaining 2 cases, changes in the dose level were made in middle course of treatment. The efficacy rate in the 1 g regimen was 76.5% and that with the 1.5 g regimen was 90%. The overall results in the 29 cases included 23 effective, 4 slightly effective and 2 ineffective cases, thus the overall efficacy rate was 79.3%. As pathogens, 11 species including 24 strains were isolated and identified from 19 cases. They were Gram-positive cocci including 2 strains each of Staphylococcus aureus and Streptococcus pneumoniae, 1 strain each of Staphylococcus epidermidis, Streptococcus sanguis, and Streptococcus viridans and a strain of Streptococcus spp., and Gram-negative rods including 9 strains of Pseudomonas aeruginosa, 4 strains of Haemophilus influenzae and 1 strain each of Klebsiella pneumoniae, Enterobacter cloacae and Pseudomonas spp.(ABSTRACT TRUNCATED AT 400 WORDS)

Adult↗
PubMed1991

The surgical treatment of a thoracoabdominal aortic aneurysm with total preservation of the intercostal and lumbar arteries using a permanent bypass technique--a case report.

A 44 year old man underwent successful surgery for a thoracoabdominal aortic aneurysm using a permanent bypass graft and aneurysmoplasty. This technique reduces visceral ischemia to a minimum and the aneurysmoplasty, through total preservation of the intercostal and lumbar arteries, can avoid paraplegia caused by spinal cord ischemia. Our technique is recommended as it can be performed easily, safely, and effectively without heparinization, temporary shunts or bypass perfusion.

Abdominal Muscles↗
PubMed1991

[A case of mitral stenosis associated with cardiac sarcoidosis and left ventricular aneurysm].

We report a rare case of mitral stenosis associated with cardiac sarcoidosis and left ventricular aneurysm. A 60-year-old female was admitted with complaint of palpitation and dyspnea on exertion. Chest X-ray revealed cardiomegaly and pericardial calcification, but no bilateral hilar lymphadenopathy. Electrocardiogram showed various arrhythmia. Coronary angiography showed no stenosis in any coronary arteries. Cardioangiogram showed left ventricular aneurysm at the apex and mitral stenosis. Laboratory findings showed no evidence of sarcoidosis. Open mitral commissurotomy and left ventricular aneurysmectomy was performed. Pathological findings of the myocardium showed a remarkable degenerative change and a granulomatous inflammation. Postoperative biopsied specimens of right scalene lymph nodes revealed sarcoid reaction. The postoperative course was satisfactory, but arrhythmia remained. The patient was treated with steroids and pacemaker implantation. She has been doing well for 2 year postoperatively. An operative case of mitral stenosis associated with cardiac sarcoidosis and ventricular aneurysm due to sarcoidosis is very rare and the prognosis in patient is very poor usually.

Cardiomyopathies↗
PubMed1991

[A case report of type II dissecting aneurysm after aortic valve replacement, successful repair by the modified Cabrol's method].

A case of type II dissecting aneurysm after aortic valve replacement was reported. The patient was a 66-year-old man, who was diagnosed as III degree aortic valve regurgitation without aortic dilatation, and performed aortic valve replacement with a 27A Omniscience prosthesis. Postoperative course was very smooth for 7 years, however he was admitted to our hospital of the sudden anterior chest pain. Computed tomography and aortography revealed marked dilatation and dissection of ascending aorta and occlusion of the right coronary artery. The operation of the modified Cabrol's method was performed, and he is well alive one and half a year after operation. Dissecting aneurysm in the late term after aortic valve replacement is rare, and its prognosis and re-operative results are very poor.

Aged↗
PubMed1990

Left ventricular rupture following mitral valve replacement--a report of two cases.

Left ventricular rupture is a rare and usually fatal complication of mitral valve replacement, and we report herein, 2 successfully treated cases of type III left ventricular rupture. The laceration in the posterior ventricular wall was repaired by a wide buttressed mattress suture with teflon felt belts on either side, then covered with Oxycel and fibrin glue or a large patch and fibrin glue. Naturally, the operation must be performed carefully and gently, however, the most important etiologic factor of left ventricular rupture is the extremely friable myocardium due to aging and a long history of heart disease. Utilizing fibrin glue for successfully repairing the rupture proved very effective.

Aged↗
PubMed1989

Use of a new stapling instrument for permanent occlusion of the aorta in the surgical procedure for thromboexclusion.

Permanent aortic occlusion is required in the surgical procedures for the flow reversal and thromboexclusion technique and also for the permanent exclusion of aneurysms of the thoracic aorta. We have designed a stapling instrument for the permanent occlusion of the aorta and have used it in 5 patients with aortic dissections and 2 patients with aneurysms of the thoracic aorta. This report describes our newly designed surgical stapler for the closure of the aorta with 2 case reports.

Aortic Dissection↗
PubMed1989

Granulocytosis associated with malignant neoplasms: a clinicopathologic study and demonstration of colony-stimulating activity in tumor extracts.

We studied seven cases of malignant neoplasms, taken from various sites in the body, that were associated with marked granulocytosis. The seven cases were characterized clinically by marked granulocytosis with mature neutrophils, nonspecific inflammatory signs, and a rapid and progressive fatal course of the disease. The elevation of granulocyte count generally paralleled the increase in tumor size. Postmortem examination revealed no evidence of extensive bone marrow metastases or significant suppuration in any case. The bone marrows showed varying degrees of granulocytic hyperplasia with or without a shift to the left in the maturation series. Erythroid cell hyperplasia was observed in some cases, and in one instance there was an increase in immature eosinophils. The spleen showed various degrees of infiltration by neutrophils, from minimal to extremely marked; some spleens had foci of extramedullary hemopoiesis. Colony-stimulating activity was demonstrated in tumor extracts from three of these cases and from the serum in another case. Thus, it is suggested that marked granulocytosis in these patients was caused, at least in part, by colony-stimulating factor produced by the neoplastic cells.

Adult↗
PubMed1989

[Role and significance of extended operation in the treatment of stage IV carcinoma of the esophagus].

A total of 106 cases of esophageal cancers treated in our hospital between Jan. 1980 and Jan. 1989 were studied to evaluate the role and significance of extended surgical resection in the treatment of the stage IV patients with T3 tumors. Of those treated were included six patients of stage 0, four of stage II, twenty-nine of stage III, and fifty-two of stage IV. Resectability rate was 82.1%, direct death rate was 8.0%. An overall one-year and three-year survival rate were 54.0% and 21.8%, and those of stage IV were 26.6% and 6.4% respectively. For thirty-one of the 52 patients with T3 tumor, combined radical resection of the structures were performed, with a mortality rate of 12.9%, and a mean survival period of 720.2 days for n0, 239.5 days for n2 (+) and 299.4 days for n3-4 (+). Mean survival of the patients without combined resection of the involved structures were 465 days(n0), 156 days(n2) and 236 days(n3-4) respectively. The organs resected included the trachea(17), thoracic aorta(7), carotid artery(4), pericardium(4), lung(3) and so on. It is concluded that improved survival for even advanced T3 carcinomas especially without lymph nodes metastasis might be obtained by the combined radical resection of the involved neighboring structures.

Esophageal Neoplasms↗
PubMed1989

[Three staged operation for aneurysms of abdominal thoracoabdominal and aortic arch].

Sixty-one year old man, who was diagnosed as abdominal and thoracoabdominal aortic aneurysms, underwent only Y graft replacement for abdominal aortic aneurysm. Two years later, the graft replacement was carried out for the thoracoabdominal aortic aneurysm. Three years after the second operation, graft replacement of the aortic arch was performed under separate cerebral perfusion technique as a supportive measure, because of the gradual growth of the arch aneurysm. We recommend the distal aneurysm (abdominal aortic aneurysm) should be removed first to prevent the detachment of the thrombus in the aneurysm during proximal operation.

Aorta, Abdominal↗
PubMed1989

[Successful surgical treatment of incomplete type IB2 cor triatriatum (absent left innominate vein) with coronary sinus atrial septal defect].

The combination of type IB2 cor triatriatum and coronary sinus ASD is very rare in congenital heart condition. Up to present, only one case of IB2 cor triatriatum and thirteen cases of coronary sinus ASD were reported in Japan. In this combination, we have presented the first successful surgical treatment for type IB2 cor triatriatum (Lucas-Schmidt's classification), absent left innominate vein and coronary sinus ASD. The patient was a 52-year-old female admitted with chronic dyspnea. Echocardiography and cardiac catheterization revealed ASD, severe mitral regurgitation, cor triatriatum, left SVC connected to left atrium (accessory chamber) and absent coronary sinus. Under cardiopulmonary bypass she underwent surgical treatment which consisted of a resection of the intra-left-atrial diaphragm, closure of ASD with patch, mitral valve replacement with Omnicarbon #29 valve and ligation of left SVC. Her postoperative course was uneventful.

Brachiocephalic Veins↗
PubMed1989

Abdominal aortic aneurysm in a 3-year-old child: a case report and review of the Japanese-language literature.

A case of abdominal aortic aneurysm associated with renovascular hypertension in a 3-year-old boy is reported. The child was treated by resection of the aneurysm and replacement with a 12 mm polyester (Dacron) bifurcated graft. The cause of the aneurysm was not revealed by clinical and pathologic examination. In addition to the case report, the Japanese-language literature is reviewed. The most frequently reported etiologic factor was Kawasaki disease; we could not find any evidence of connective-tissue disorder as a cause for abdominal aortic aneurysms occurring in children.

Aorta, Abdominal↗
PubMed1989

[Bypass operation adaptable to stature increase in child with atypical coarctation of the aorta].

A 9-year-old girl was admitted with hypertension and severe congestive heart failure. Upon physical examination, a discrepancy of blood pressure between arm and leg was noted. Aortography revealed narrowing about 5 cm in length at the midportion of the descending thoracic aorta. Bypass operation of the narrow segment was performed under mild hypothermia with the diagnosis of atypical coarctation of the aorta. It was supposed that the patient might outgrow the graft and the graft would become too small for grown-up patient in diameter and length, then the haemodynamics would become less satisfactory and too much tension on the suture line would occur. A woven Dacron graft, 10 mm in diameter, 15 cm in length, was anastomosed proximally and distally to the coarcted segment at a distance of about 6 cm. So, the graft was disposed in a C-shaped configuration. It was expected that the arch of the graft would open more widely with increase of her stature, even if the graft does not increase in length. She has been followed for twelve years. Hypertension of upper extremity and arm-to-leg gradients of the systolic blood pressure were recognized from two years after the operation, particularly with exercise. However, cardiomegaly and left ventricular hypertrophy in ECG were improved. She appears to have been developing normally with no cardiac symptoms. Estimating from angiography, the distance between proximal and distal anastomoses stretched about 2 cm during the period of rapid growth, though calcification of the graft had been seen from four years after the operation, perhaps due to increased calcium turnover in childhood.

Aorta, Thoracic↗
PubMed1989

[A simultaneous operation of closure of multiple congenital coronary artery-pulmonary artery fistulas and aortocoronary bypass grafting--a case report].

A 59-year-old male was admitted because of severe chest pain and diagnosed as inferior myocardial infarction by ECG and enzymologically, who had a Levine grade II continuous murmur in the left second intercostal space at the left sternal border. Cardiac catheterization revealed a 8% left to right shunt at pulmonary artery. Selective coronary cineangiography revealed left anterior descending-to-main pulmonary artery and left circumflex-to-main pulmonary artery fistulas, and severe atherosclerotic stenosis at right coronary and left anterior descending arteries. Operation was performed simultaneously, closure of two drainage orifices of the fistulous vessels through pulmonary arteriotomy and aortocoronary bypass grafting to left anterior descending under cardiopulmonary bypass. The postoperative course was uneventful, and the murmur was disappeared.

Arterio-Arterial Fistula↗
PubMed1989

[Clinical examinations of thymic abnormalities and significance of thymectomy in the patients with autoimmune disease].

Results and significance of thymectomy in 427 patients with autoimmune disease, which include myasthenia gravis, ulcerative colitis. Behçet's syndrome and others, were studied. Preoperative pneumomediastinography was useful to delineate the outline of the nontumorous thymus and small "latent thymoma". The thymus was almost always successfully removed by our procedure "thymectomy via the suprasternal notch" (Method I), but the procedure combined with dissection through a parasternal incision (Method II) was frequently performed. Method II has been routinely adopted since 1976. Thymectomy was performed on a series of 180 patients with myasthenia gravis associated with nontumorous thymic abnormalities. In the resected thymuses, lymphoid follicle formations, which are often encountered in other autoimmune diseases, were found in 74% of cases. Follow-up observation, ranging 2 to 17 years after surgery, revealed complete recovery and significant improvement in 100 (75%) out of 133 patients with nontumorous thymic abnormalities. Thymectomy was also performed in 44 myasthenia gravis patients with thymoma, including 13 small "latent thymoma". Seventy-seven thymectomized patients with ulcerative colitis were also studied, and in these resected thymuses lymphoid follicle formations were fond in 45%. Follow-up observation revealed 84% inactive condition (counted by patient year) after thymectomy compared with 50% before operation. In the patients with Behçet's syndrome, recurrence and progression of skin, oral and genital lesions were markedly suppressed after thymectomy.

Adolescent↗
PubMed1989

[The use of the aortic bypass in the surgery of the esophageal carcinoma invading the thoracic aorta].

During the period from 1980 to 1989, five patients with carcinoma of the esophagus invading the thoracic aorta were treated by resection of the involved aortic segment combined with esophagectomy. Various types of arterial bypass were applied in order to provide blood flow to the distal aorta during aortic clamping. These included one permanent aorto-aortic bypass, two axillo-femoral bypass and one subclavian-aortic bypass. There was one death within 30 days and one developed paresis. These arterial bypasses are beneficial to esophageal surgery because it is technically easy and it does not necessitate systemic heparinization which maybe associated with profuse bleeding.

Aged↗
PubMed1989

[Evaluation of myocardial protection with DBcAMP in crystalloid cardioplegic solutions].

The potential for myocardial protection during cardiac operation was evaluated by adding Dibutyryl cyclic AMP (DBcAMP) to the crystalloid cardioplegic solutions. We have compared the cold crystalloid cardioplegia with DBcAMP (Group D n = 15) and without DBcAMP (Group n = 20) in patients undergoing cardiac operation. In hemodynamics, both groups were no difference before and after operation. CPK and CPK-MB was significantly (p < 0.01) high level after cardiopulmonary bypass (CPB) in group C. Myoglobin was also high value after CBP in group C, but not significant. Myocardial oxygen extraction rate and coronary blood PCO2 release were similar change in both groups. Insulin/glucose ratio was high level during and after CBP in group D. Myocardial lactate/pyruvate ratio was very high level after CBP in group C without significant difference. We consider that the cardioplegic solution with DBcAMP is effectual for the myocardial metabolism and preservation of myocardial damage during cardiac arrest.

Adult↗