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Biomedical subjects

S Owitz

Publications and source records attributed to S Owitz.

9 recordsLinked to original sources
PubMed1980

Sympathetic nervous system tonicity and post-coronary artery bypass hypertension.

To elucidate the pathogenesis of hypertension following coronary bypass surgery, blood pressure and plasma catecholamine concentration were measured in 28 patients with coronary artery disease who were undergoing myocardial revascularization procedures. Measurements were obtained on arrival in the operating room and 1 and 4 h after surgery. One hour after surgery, plasma norepinephrine (NE) increased significantly by 495 +/- 108 pg/ml (P less than 0.001) in the coronary artery disease group which developed hypertension, but the increase was not significant in the coronary artery patients who remained normotensive after surgery. However, 4 h after surgery, plasma NE increased significantly and to the same extent in both coronary artery disease groups, regardless of the change in blood pressure. Plasma epinephrine (E) also increased significantly 1 and 4 h after surgery in both groups. The observed change in plasma catecholamine concentration is direct evidence that the stress of surgery is a potent adrenergic stimulus, but the hemodynamic significance of the plasma catecholamine change remains unclear.

Blood Pressure↗
PubMed1979

Anaesthetic considerations in the prolonged Q-T interval (LQTS): a case report.

A case of prolonged Q-T interval syndrome (LQTS) with ventricular dysrhythmias is presented. The patient was unresponsive to medical treatment. Left stellate ganglion block, followed by surgical excision of the ganglion, resulted in reversion to normal sinus rhythm. The causes of LQTS, its treatment and the effects of anaesthetic agents are discussed.

Adult↗
PubMed1978

The cerebral function monitor during open-heart surgery.

Open-heart surgery has entered the third decade of its existence. The period has demonstrated increased patient safety during and after open-heart surgery due to the employment of simple and reliable monitoring techniques. The monitoring of the function of the brain has not kept pace with these advances. Electroencephalographic (EEG) method is impractical for routine use in the operating room and in the intensive care unit. The cerebral function monitor (CFM) offers simplified continuous monitoring and interpretation of cerebral electrical activity (integrated EEG) in the clinical situation. The unit displays a two channel tracing, one representing cerebral activity and a second indicating electrode impedance artefacts. The early changes seen in addition to other conventional monitoring of the electrocardiogram, blood pressures, pulse rate, etc. offers information especially pertinent to open-heart surgery. It would appear that there is a place in anesthetic practice during and after cardiopulmonary bypass for the routine use of the CFM to supplement existing monitoring for the safer conduct of open-heart surgery. This study analyzes the value of a cerebral function monitor in 112 patients undergoing open-heart surgery.

Brain↗