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Biomedical subjects

S P Garg

Publications and source records attributed to S P Garg.

At least 19 recordsLinked to original sources
PubMed1997

Endogenous cortisol profile in patients with central serous chorioretinopathy.

AIM: To study the endogenous cortisol levels in patients with central serous chorioretinopathy (CSCR). METHODS: Endogenous cortisol levels in urine and plasma were determined in 30 patients with acute CSCR and compared with 30 age and sex matched controls. RESULTS: The mean values of the 8 am plasma cortisol (29.97 micrograms/dl v 18.76 micrograms/dl), 11 pm plasma cortisol (22.03 micrograms/dl v 13.06 micrograms/dl), and 24 hour urine cortisol (11.01 mg/24 h v 7.39 mg/24 h) revealed significantly higher values in the patient group (p < 0.001). CONCLUSIONS: Increased levels of endogenous cortisol are present in patients with CSCR.

Adult↗
PubMed1994

Neodymium: YAG laser iridolenticular synechiolysis in uveitis.

Fifteen patients with "bound down" pupil or ring synechiae associated with chronic granulomatous uveitis in whom dilatation could not be obtained pharmacologically underwent iris-lens synechiolysis using relatively low energies from a Q-switched Nd:YAG laser. Pupil size increased significantly in all of the treated eyes; visual acuity improved in 40%. Postlaser elevated intraocular pressure developed in a significant number, but there were no serious long-term complications associated with the procedure. Although acuity improved in less than half of the patients, because this laser treatment is relatively safe and offers some possibility of visual improvement, we recommend it for routine use, but only if performed by an experienced laser microsurgeon.

Adult↗
PubMed1991

Serous macular detachment in lymphoproliferative disorders.

Two patients, one with Hodgkin's disease and the other with non-Hodgkin's lymphoma, presented with bilateral diminution of vision. Examination showed bilateral serous detachment of the macula. To our knowledge, this is only the second report in the literature of serous detachment of the macula in lymphomatous disorders.

Adrenal Cortex Hormones↗
PubMed1991

Metastatic endophthalmitis: a reappraisal.

In view of the lack of studies of metastatic endophthalmitis and the controversies surrounding its management, we did a retrospective study of ten cases of metastatic endophthalmitis admitted to our center in 1987. A disproportionately high incidence of pediatric patients was found. The etiologic diagnosis was possible in eight of the ten cases. Bacterial infection was responsible in five of the eight cases where positive cultures were grown. Pseudomonas aeruginosa was the most common bacterial pathogen isolated. Most of the cases responded poorly to medical management. Seven of the ten patients finally underwent vitrectomy. Four of these seven cases had a postoperative visual acuity equal to or greater than 6/60 after vitrectomy. We believe that pars plana vitrectomy has a definite role in the management of metastatic endophthalmitis.

Adolescent↗
PubMed1990

Pupillary dilatation during cataract surgery--relative efficacy of indomethacin and flurbiprofen.

In a prospective, randomized, double-blind trial, we evaluated the relative efficacy of indomethacin and flurbiprofen when used as adjuvants to routinely used mydriatics for maintenance of pupillary dilatation in patients with heavily pigmented iris undergoing extracapsular cataract extraction. The drugs were administered orally as well as topically according to a fixed regimen. The pupillary diameters, measured with calipers at various surgical steps, were significantly larger at every step in the study groups in which either of the adjuvants had been used than they were in the control group (P less than .001). Flurbiprofen tended to help maintain a larger pupillary diameter in the later stages of surgery than indomethacin, but this difference was not statistically significant. We conclude that it is important to use prostaglandin synthetase inhibitors as adjuvants to routine mydriatics, and that flurbiprofen may be somewhat more effective than indomethacin in this capacity.

Cataract Extraction↗
PubMed1989

Chlamydial serology in uveitis.

Ninety seven sera, 53 from patients with Acute Anterior Uveitis and 44 from age and sex matched controls were tested for antichlamydial antibodies employing a recently developed technique of ELISA. Higher positivity of 27.0% was recorded in controls as against 17.0% in patients. The difference was statistically insignificant. All the subjects had trachoma at stage II-IV. Age and sex did not seem to influence the findings in both, the cases and controls. Through this study, the role of Chlamydia in the etiology of A. A. U. is not ascertained. Further studies are recommended.

Adolescent↗
PubMed1988

The role of environmental factors and hereditary predisposition in the causation of low myopia.

Various environmental factors have been implicated in the etiology of myopia. An attempt was made quantitatively to estimate some such environmental factors, as based on the presence or absence of a family history of myopia. Age range was 10-21 years. The 200 subjects included in the study were further divided according to emmetropia/myopia. The factors studied in the four subgroups were amount of near work done per day, head posture and illumination level while doing near work, acute fevers, chronic illness, acute or recurrent diarrhea, nutritional status, and income levels. A correlation was found between myopia and near work, head posture and income levels.

Adolescent↗
PubMed1988

Increased mitral valve insufficiency during precordial "whoop".

A patient with rheumatic mitral valve stenosis and regurgitation presented with shortness of breath and a "noise" in her chest. Cardiac auscultation revealed an intermittent late systolic "whoop." An increase in severity of mitral valve insufficiency during the periods of "whoop" was observed by pulsed Doppler, hemodynamic tracings and left ventriculography.

Aged↗
PubMed1987

Bilateral disc oedema in retinitis pigmentosa--an unusual sign.

An unusual case of Bardet-Biedl syndrome which presented with sudden total visual loss in both eyes is documented. The fundus picture and angiographic findings were consistent with the diagnosis of bilateral disc oedema with retinitis pigmentosa. The various etiological possibilities resulting in the manifestation of bilateral disc oedema in this case of retinitis pigmentosa are considered. Inflammatory disc oedema secondary to photoreceptor degeneration as a possible cause of acute loss of vision in retinitis pigmentosa is discussed.

Adult↗