Biomedical subjects
S P Lorton
Publications and source records attributed to S P Lorton.
Hyaluronidase does not disperse the cumulus oophorus surrounding bovine ova.
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Mechanisms controlling motility of stallion spermatozoa.
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Inhibition of sperm migration through cervical mucus in vitro.
The effectiveness of inhibiting bovine sperm migration through cervical mucus in vitro by prior treatment of semen with 45 to 150 micrograms of soybean trypsin inhibitor, univalent (papain-digested, nonagglutinating) and bivalent (undigested) rabbit anti-bovine sperm immunoglobulin, and heat-treated heifer serum was studied. Sperm head-to-head agglutination resulted from treatment of semen with bivalent immune antibody and heat-treated heifer serum. Migration through cervical mucus was inhibited only by treatment resulting in spermagglutination. It is postulated that in vivo inhibition of sperm migration may be influenced by secretory immunoglobulins from the cervix.