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Biomedical subjects

S P Raskin

Publications and source records attributed to S P Raskin.

7 recordsLinked to original sources

The pulmonary acinus: historical notes.

While the pulmonary acinus as an anatomical unit is central to an understanding of pulmonary disease, its radiographic validity remains in doubt. A review of the historical basis of present knowledge about the acinus reveals several sources of confusion. It is suggested that recent findings provide better justification for the use of this term than historical sources.

Anatomy, Comparative↗

Recognition of lumbar disk disease: comparison of myelography and computed tomography.

A retrospective study was devised to determine the correlation between myelography and computed tomography (CT) in the recognition of abnormalities of the lumbar intervertebral disk. A group of 106 patients was studied who had had both myelography and CT within a 6 week period. Each examination was interpreted separately by a neuroradiologist who had no access to the patients' clinical findings or the results of any radiologic studies. On comparison of 290 interspace levels, there was agreement in definite abnormalities in 70%. Most discrepancies were due to suspicious findings and inconclusive studies of both kinds. In particular, there was poor correlation between the two examinations in the diagnosis of a slightly bulging disk. The major discrepancy rate was less than 5% overall and less than 1% among patients without prior surgery. On the basis of these findings, a diagnostic algorithm is suggested that would facilitate the workup of a similar group of patients.

False Negative Reactions↗

Demonstration of nerve roots on unenhanced computed tomographic scans.

Small foci of high attenuation are seen within the subarachnoid space on high resolution axial transverse computed tomography (CT) of the lumbar spine. By use of reformatted images in oblique planes, these foci form linear structures of high attenuation corresponding to the nerve roots of the cauda equina. Unenhanced CT is therefore capable of demonstrating the nerves of the cauda equina in selected cases.

Adult↗

Interacinar pathways in the human lung.

Normal lung specimens from patients 18 to 86 years of age were inflated, fixed, and cleared. After micropuncture of the distal airspaces and injection of silicone rubber, the dissemination pattern was studied by cinematography. Free interacinar flow was commonly observed. The major pathways of spread among adjacent acini were the interacinar ducts. These were short, tubular structures 200 mum in diameter that were continuous with respiratory bronchioles and alveolar ducts. The flow of silicone rubber was impeded only by the septa of the secondary lobule of Miller. Our finding support the view that the smallest morphologic unit of airspace disease is more likely to be the secondary lobule than the acinus.

Adolescent↗