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Biomedical subjects

S Palma

Publications and source records attributed to S Palma.

36 records · Page 2Linked to original sources

[Sacroiliac infection: clinical characteristics in 11 cases].

We report clinical and laboratory findings in 11 patients with septic sacro-iliitis. Fever, pain and immobility were prominent symptoms. Acute tenderness of the sacroiliac joint and elevation of the ESR were present in all. Joint puncture allowed identification of the infectious agent in 10 patients: S aureus 4, S typhi 3, E coli 2 and P mirabilis 1. Good clinical results were obtained after appropriate antibiotic therapy.

Adolescent↗

The tip of the iceberg: a validation study of the Victorian Congenital Malformations/Birth Defects Register.

Among 1500 children under 4 years of age admitted consecutively to two paediatric teaching hospitals in Victoria in 1985 the prevalence of birth defects was 20%. Fewer than half of these defects had been notified to the Victorian Congenital Malformations Register. Only chromosomal anomalies and, to a lesser extent, major structural malformations present at birth were adequately ascertained. The implications for birth defects monitoring and for service planning are discussed.

Child, Preschool↗

[Behçet's disease].

Explore the source record for details and available documents.

Adrenal Cortex Hormones↗

Efficacy of flecainide in the management of ventricular arrhythmias: comparative study with amiodarone.

The effects on ventricular arrhythmias of a new class IA drug, flecainide, were compared with those of amiodarone in 10 patients with frequent, chronic, and stable ventricular ectopic beats (VEBs). The study consisted of an initial 1-week, placebo-controlled, baseline period followed by two 12-day, randomized, crossover, double-blind treatment periods with incremental dosage and 1 month of placebo between drug periods. Frequent VEBs, which were present in all 10 patients during both placebo control periods (30 or more VEBs/hour every hour, during 24-hour Holter monitoring), were markedly suppressed (reduction greater than 80%) in nine patients with both drugs (p less than 0.01). There was almost total abolition of the VEBs in six patients with flecainide, and the satisfactory results with a minimal dose in three demonstrate its fast onset of action. Side effects from either agent were infrequent and no discontinuation was necessary. We conclude from our study that flecainide is a highly effective antiarrhythmic agent.

Adult↗

Prevalence of myopia in open angle glaucoma.

In this study concerning the prevalence of myopia in patients with open angle glaucoma, its distribution was analyzed within the sample tested in relation to the refraction defect size, compared with a control group of non-glaucomatous myopic subjects. The overall myopic rate was 17.2% of the glaucomatous patients; high myopia was more frequent in the subjects with open angle glaucoma (p less than 0.001) than in the myopic patients, thus appearing as a possible risk factor for the development of glaucoma.

Adult↗

Validation of the Victorian Perinatal Morbidity Statistics form: new items, pre-coded text and free text.

This study assessed the quality of information on the form used by the Victorian Perinatal Data Collection Unit. Information relating to four new and one modified data items, and to pre-coded and free text regions relating to maternal morbidity, was compared with that in the medical record. The new data items were documented correctly on 95.5% of forms, as were 67% of pre-coded conditions. Between 53% and 75% of free text items were correctly recorded. The results highlight the need for information and education sessions for midwives and other staff in order to collect and maintain high quality data.

Congenital Abnormalities↗

Determinants of the interval between diagnosis and treatment in patients with digestive tract cancer.

The main objective was to analyze the influence of social factors on the interval from diagnosis to treatment in a cohort of 217 patients with digestive tract cancer. From the clinical charts data were obtained for: date of the beginning of illness, dates of medical attendance, type and date of diagnostic tests, characteristics of the disease (symptoms, stage), and date of treatment. From the personal interview we gathered information lacking in the clinical charts such as socio-demographic factors, other underlying diseases, and variables related to life style. The information on hospital admission, diagnosis, and treatment was prospectively gathered, whereas data before hospitalization were retrospectively assessed. In statistical analysis the Kruskal-Wallis test and Cox regression were used. The predictors associated with a shorter diagnosis-treatment period were: low social class, lymphatic involvement at diagnosis, first visit at secondary/tertiary level of health care, no car availability, two or more symptoms at the beginning of disease, sex (male), age (less than 74 years), and diagnosis out of vacation periods. In conclusion, several socio-demographic variables (age, gender, social class, and car availability) influence the interval diagnosis-treatment.

Aged↗