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S Papagni

Publications and source records attributed to S Papagni.

4 recordsLinked to original sources
PubMedDate not supplied

[Determination of bone mineral content and correlations with calciotropic hormones in periodic hemodialysis patients].

The investigation on several forms of uremic osteodystrophy by means of bone mineral content (BMC) measurement led to contradictory conclusions. BMC in 27 patients on periodical hemodialysis treatment was measured correlating it to the seric levels of Ca, P, Mg, alkaline phosphatase (AP), calcitonin (Ct), osteocalcin (BGP), intact parathormone (PTHi), c-terminal and mean molecule PTH. Patients on dialysis treatment from a long period of time showed high AP and low BMC levels. This correlation proved significant just for the values recorded at a third distal site of radius. Patients with BMC under the normal range showed higher BGP levels and a longer period of dialytic treatment than those presenting normal BMC. The former showed a Ct inverse correlation as to age and mineralization indexes. Higher values of Ct and BMC have been reported in males rather than in females. Hence BMC is not suited to investigate different kinds of uremic osteodystrophy. Seric PTH dosage is certainly best fitted to discriminate patients affected with hyperparathyroidism from those with low turnover osteodystrophy. BMC determination is a valid support to evaluate the bone mineral loss in patients on haemodialysis treatment. It significatively correlates to the duration of the dialytic treatment; it is higher in female than in male population; it mainly affects cortical components rather than trabecular ones and is related to a seric Ct decrease.

Adult↗
PubMedDate not supplied

[Quality in dialysis].

BACKGROUND: Several clinical and laboratory dialysis parameters have been suggested by national and international guidelines. Our study aimed to evaluate a series of quality indicators in the dialytic treatment of a group of patients in our two dialytic centers. PATIENTS AND METHODS: In a population of 159 patients on renal replacement therapy (RDT) we performed a 1-yr prospective observational study, with common parameters to indicate cardiovascular pathologies (PAS, LVMI), calcium-phosphorous metabolism (Ca, PO 4 , Ca x PO 4 ), dialytic adequacy (Kt/V, URR%), nutritional status (nPCR, Alb, K), and anemia (hemoglobin (Hb)). For each parameter we evaluated the mean average with the standard deviation and the score percentages below and above the acceptable range (AR). RESULTS: The results demonstrated a substantial stability, with a gradual improvement, in dialytic adequacy, in anemic status and in PAS. The LVMI, calculated at the beginning and at the end of the period, did not demonstrate any significant changes. No significant changes were observed in the calcium-phosphorous metabolism parameters. Serum albumin and nPCR demonstrated the presence of malnutrition in 15-20% of patients. CONCLUSIONS: There was a more than adequate correlation between the target guidelines and that concerning the dialytic adequacy and the corrected anemic status. The improvement in parameters related to cardiovascular pathology, the risk of ectopic calcifications and malnutrition status, represented an achievable target.

Female↗
PubMedDate not supplied

Brain tumor death risk in mental patients.

Several investigators have previously reported a low cancer mortality in mental patients. They hypothesized there were possibilities of actual exclusion between cancer and psychosis. On the other hand, some Authors warned that the reported association between psychiatric illness and cancer death might vary, depending on the used statistical methods. To clarify this problem, we have examined the incidence of deaths caused by malignant neoplasm, particularly from brain tumor, in the chronic patients of Bisceglie Psychiatric Hospital, evaluating either absolute or relative mortality rate analysis. Our results seem to suggest an increased absolute mortality from malignant brain tumor in mental patients.

Adult↗