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S Partoft

Publications and source records attributed to S Partoft.

10 recordsLinked to original sources
PubMed1999

Prestorage leukocyte filtration may reduce leukocyte-derived bioactive substance accumulation in patients operated for burn trauma.

Adverse effects of perioperative blood transfusion appear to be storage-time-dependent and may be related to extracellular accumulation of bioactive substances in blood products. In this study the clinical effects of leukofiltered and non-filtered blood products in patients undergoing surgery for burn trauma are investigated. 24 consecutive patients were randomly selected to receive transfusion with non-filtered blood components (group A, n = 12) or similar products, which were prestorage leukofiltered (group B, n = 12). The burn injury was scored using the Bull and Fischer index of age and burn surface area. Histamine, interleukin-6 (IL-6), plasminogen activator inhibitor-1 (PAI-1), eosinophil cationic protein (ECP) and myeloperoxidase (MPO) were analysed in plasma or serum collected from all patients 30 min before skin incision, at skin incision and 5, 10 and 30 min and thereafter every 30 min after skin incision until the grafts were secured by wrapping. Samples were also taken 8 h after skin incision and in the morning of postoperative days 1-5. The amount of blood products transfused from admission until day 5 postoperatively was recorded. All patients were followed until discharge or death. The Bull and Fischer index was comparable in the two groups. Prestorage leukofiltration reduced the amount of blood products required for transfusion significantly (p < 0.05) compared with non-filtered products. The levels of the various bioactive substances changed during and after the operation. In particular, ECP and MPO levels increased significantly (p < 0.05) in group A patients compared with unchanged (ECP) or decreased (MPO) levels in group B patients. IL-6 analyses showed, that the trauma had more severe impact on group B patients than on group A patients. Nevertheless, 4 patients died in group A and 2 in group B; all with a Bull and Fischer index between 1.0 and 2.0. Prestorage leukocyte filtration may reduce transfusion related accumulation of various bioactive substances and the requirement for blood in burn trauma patients.

Adult↗
PubMed1997

[Electric injuries--cardiac monitoring?].

During the years 1980-1990, 49 patients (38 men and 11 women) were treated in the department for various electrical injuries. The average age was 27 years (2-78 years). Thirty-nine had suffered low voltage (less than 1000 volts) accidents and ten had suffered high voltage (more than 1000 volts) accidents. The incidence and type of cardiac arrest/loss of consciousness on the scene of the accident, myoglobinuria, acute fasciotomies, surgical interventions, amputations, cardiovascular complications and outcome is reported. The most important finding was that no cardiac abnormalities were seen even with the patients with a clinical primary cardiac arrest. In spite of this finding 18 of the patients were initially brought to a medical department for electrocardiographic monitoring. This could clearly delay surgical intervention, though it did not seem to affect the final outcome (with some reservations). It was concluded that only abnormal ECGs should indicate electrocardiographic monitoring. Otherwise an electrical injury is a surgical matter.

Accidents↗
PubMed1991

[Plastic surgical reconstruction in microtia. A follow-up study].

During the period 1967-1987, 26 ear reconstructions were carried out in the Department of Plastic Surgery, Rigshospitalet, Copenhagen. These 26 patients were followed up, partly from the hospital records and partly by means of a questionnaire. Twenty-two patients replied to the questionnaire. The average age was 8.8 years at the commencement of the reconstruction and the average duration of hospitalization was 41 days. The reconstructions employed autologous costal cartilage. Minor complications were observed in approximately half of the patients. One patient developed pneumothorax postoperatively and one lost the grafts on account of repeated infections. 77% of the patients stated that the operation had been worthwhile. 37% found the result disappointing while the remaining 63% considered that the results were better than they had anticipated or as they had anticipated. The operation had no effect on teasing by peers. It is concluded that ear reconstruction should be postponed till an older age and that thorough preoperative information to the patients is important. The operation of surgical ear reconstruction is regarded as a valuable offer to patients with microtia.

Child↗
PubMed1991

[Gynecomastia treated by subcutaneous mastectomy using Webster's method].

Gynecomastia was treated surgically by Webster's method in 23 patients during the period from 1983 to 1989. This surgical procedure was used if gynecomastia was classified from stage 1 to stage 2B. Cosmetic reasons were the major reasons for operation in 70% of the patients. The most common late postoperative sequelae were inverted areolae and hypaesthesiae of the areolar region. When operation was carried out, half of the patients were overweight. The remainder were of normal weight. Among the patients, who were overweight time of operation, 2/3 found that the cosmetic correction was unsatisfactory. In the "normal weight group" 2/3 were satisfied with the cosmetic result. The patients in the dissatisfied group found that too little tissue had been removed from the area. The operation is carried out through a little infraareolar incision. Because of this, it is technically difficult, especially in patients with considerable subcutaneous tissue. On this background, we find that Webster's method alone, not should be used as surgical treatment of gynecomastia in overweight patients.

Adolescent↗
PubMed1989

Malignant melanoma of the skin in children (0 to 14 years of age) in Denmark, 1943-1982.

A total of 63 cases of cutaneous malignant melanoma in children have been reported to the Danish Cancer Registry during the 40-year period from 1943-1982. In order to describe the true incidence of childhood melanoma in Denmark, a clinical and pathological evaluation was performed. Not surprisingly we found that childhood melanomas were gravely overdiagnosed in Denmark. Nine cases of childhood melanoma were identified in our material. Seven of these were aged 10 to 14 years. Two of the tumours had developed in congenital giant naevi. The crude incidence rate was estimated to be between 0.24 x 10(-6) and 0.32 x 10(-6). In Denmark this corresponds to one new case of childhood melanoma every 3 to 4 years.

Adolescent↗
PubMed1988

Patterns of the first lymph node metastases in patients with cutaneous malignant melanoma of axial localization.

At the Finsen Institute, Copenhagen, from 1971 to 1981, 134 patients were treated for lymph node metastases from primary cutaneous malignant melanoma of axial localization (e.g., in the head and neck and trunk), where metastases to regional lymph node groups were the first sign of dissemination. Due to the lack of sufficient clinical data, 27 patients were excluded from the study. Median time from excision of primary tumor to diagnosis of node metastases was 11 months. In 42 of 85 (49%) patients with truncal melanoma, the primary tumor was placed in the lymphatic water-shed areas. Two patients among this group showed bilateral simultaneous metastases to two different node groups. In the remaining 43 patients with truncal tumors located outside water-shed areas, node metastases developed in unexpected groups in seven (16%) patients. Of 22 patients with head and neck tumors, two (9%) patients demonstrated metastases to distant lymph node groups without metastases to the regional node basins.

Adolescent↗
PubMed1987

Cytostatic extravasations.

Sixty-six cases of cytostatic extravasation referred to a plastic surgery department between 1977 and mid-1985 are discussed. Doxorubicin was the most common drug involved, but a number of other drugs also caused lesions requiring surgical intervention. Operative treatment, consisting of excision of drug-infiltrated tissue followed by skin transplantation, was performed in half the patients. Significant residual damage was seen in 12 patients who had all received the drug at the elbow joint, wrist, or back of the hand. Fourteen patients were operated on late in the course of the disease, on average 10 weeks after the accident because of delayed referral. In 1983 prophylaxis was undertaken and first-aid treatment was administered, consisting of aspiration via the administration catheter. The nature of patient referrals then improved considerably. It is recommended that cytostatic treatment be given at the antebrachium, if possible, and that aspiration be attempted promptly after an accident. Manifest lesions should be operated on early, i.e., within the first week. The indication for early operation is particularly strong if a highly irritative drug has been deposited in a critical region and has caused a severe local reaction.

Adult↗
PubMedDate not supplied

Ultrasound-guided percutaneous aspiration of renal angiomyolipoma. Report of two cases diagnosed by cytology.

Two cases are reported in which the diagnosis of renal angiomyolipoma was made by ultrasonically guided aspiration cytology. Vessels, smooth muscle cells and fat were evident in the aspiration smears, in which no epithelial cells were found. Since the treatment of renal angiomyolipoma differs from that of adenocarcinoma of the kidney, the preoperative cytologic diagnosis is of great value.

Adult↗