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Biomedical subjects

S Patten

Publications and source records attributed to S Patten.

9 recordsLinked to original sources

Depression in people with first-episode schizophrenia.

BACKGROUND: Depression has been described in people presenting with first-episode schizophrenia, a group at high relative risk of suicide. METHOD: This was a longitudinal cohort study of 113 people during an acute relapse and 13 having a first episode. Follow-up occurred at three months and at one year. This report compares level of depression in the first episode and in the relapsing group. Levels of depression were assessed using the Calgary Depression Scale for Schizophrenia (CDSS). RESULTS: The median CDSS score was statistically significantly higher in the first-episode group both during the acute phase and at three month follow-up. At one year the first-episode group continued to have higher levels of depression than the multiple episode group. CONCLUSIONS: For people with a first episode of schizophrenia, depression is a major problem during the initial acute phase and during the first year of illness. In light of the high risk of suicide in this population, recognition and treatment of depression requires greater attention.

Cohort Studies↗

Gender and affect in schizophrenia.

OBJECTIVE: The objective of this study was to test the hypothesis that males with schizophrenia have more negative symptoms and females with schizophrenia have more depressive symptoms. Previous studies examining gender differences in negative and depressive symptoms in schizophrenia have been inconclusive, being limited by retrospective design and lack of suitable assessment instruments. METHOD: A consecutive series of 113 consenting inpatients meeting DSM-III-R criteria for schizophrenia (45 females, 68 males) were assessed using reliable measures of depression and negative symptoms. Negative symptoms were assessed by the Positive and Negative Syndrome Scale and depression by the Calgary Depression Scale for Schizophrenia. Ninety-two of the subjects were reassessed 3 months later. RESULTS: There were no differences in levels of negative or depressive symptoms between men and women. CONCLUSIONS: Within the limitations of the study, the results do not support the hypothesis of sex differences in negative and depressive symptoms in schizophrenia.

Adult↗

The utility of the Transtheoretical Model of behavior change for HIV risk reduction in injection drug users.

The spread of HIV among injection drug users (IDUs) is the second most common mode of transmission next to sexual contact. Although HIV infections can be prevented by changing high-risk behaviors such as needle sharing, these high-risk behaviors are highly complex. Initially developed for smoking cessation, Prochaska's Transtheoretical Model (TTM) is well-suited to the IDU population because it recognizes that chronic behavior patterns are usually under some combination of biological, social, and self-control. The objective of this article is to examine the utility of the TTM for promoting risk reduction behaviors among IDUs. This article will outline (a) the challenges of applying the TTM to IDU behaviors with respect to HIV prevention, (b) the four major components of the TTM as they relate to IDUs, (c) how risk reduction practitioners are currently using the TTM, and (d) current and future research using the TTM.

Attitude to Health↗