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S Perović

Publications and source records attributed to S Perović.

At least 19 recordsLinked to original sources

[Our experience in the Martius method of closing the vesicovaginal fistula].

Sometimes after delivery, gynecological or other surgeries, radiological therapy, or destructions of vesico-vaginal septum due to the tumor or trauma, the unnatural communication between the bladder and vagina occurs. Those are fistulas that occur after the delivery (tocogenic) caused by the prolonged delivery or some obstetrics operations. Some fistulas are high, coming from the fundus of the bladder, medium, if they come just behind the trigonum of the bladder, and low, if they are in the level of trigonum and the neck of the bladder. The purpose of this paper is to show the operative technique of elimination of medium and low vesicovaginal fistula and the results of the treatment. Material and method The elimination of the vesicovaginal fistula by original Martius technique is done through vagina. The catheter is inserted through the fistula (figure 1). Than the mucosis of the vagina is cut around the fistula and the vaginal wall is separated from the bladder. The catheter is pulled out and the fistula on the bladder is sown with resorptive stitches. Than the labia maiora nearer to the fistula is cut along from Mons Veneris to the middle and the lipoid tissue is taken with vascular pedicle (figure 2). This tissue is put between the bladder and the vagina and fixed with resorptive stitches. After that the vagina is sown by single stitches. The labia maiora that was cut is also sown by single stitches (figure 3). Than the catheter is inserted in the bladder that should stay there for four weeks. This is the method we used to make surgery in twenty patients with vesicovaginal fistula. The first one had the fistula as the result of the Caesarean section. She was operated twice through the bladder without success. The second patient was a fourteen years old girl that cut herself on the glass and damaged anal sfincter, rectum, vagina and the bladder. The fistula appeared later in the level of trigonum of the bladder. The other eighteen patients got fistula after hysterectomy. All patients were treated as described above and fistulas disappeared. The first patient had another baby a year after the operation by Caesarean section. The other patients have regular miction (figure 4 and 5). Discussion and the conclusion Vesicovaginal fistula are serous complications, for the patients and for the doctors. The only treatment of the vesicovaginal fistula is surgical. If any damage of the bladder occurs during any operation it should be treated immediately, otherwise the fistula will appear. The treatment depends of the localization of the fistula. Low fistulas and some medium and urethrovaginal fistulas should be approached through vagina and according to our experience Martius's method is very efficient. The only important thing is when the fistula is detected to wait at least for two or three months for the fistula to "consolidate" and also to cure the infection.

Adolescent↗

Long-term functional outcome of kidneys in children with urolithiasis after ESWL treatment.

The aim of this study was to determine the long-term functional outcome of kidneys in children with urolithiasis treated by means of extracorporeal shock wave lithotripsy (ESWL). The effectiveness and safety of this method in the management of pediatric urinary stone disease was also studied. This prospective study enrolled 84 children, 33 boys (age: 9.1 +/- 3.8 yrs) and 51 girls (age: 9.6 +/- 3.9 yrs), with urolithiasis who were treated using a second-generation "Siemens" Lithostar lithotriptor, in the period between 1988 and 1998. Dynamic kidney scintigraphy using (99 m)Tc-DTPA was done prior to, immediately following ESWL treatment, three months later, and again after an observation period of 12 - 67 months (38 +/- 13 months). Immediate fragmentation rate was 90 %, while the calculus clearance rate was 61 %. Glomerular filtration rate (GFR), measured by clearance of (99 m)Tc-DTPA, immediately after an ESWL treatment of 107 +/- 6 ml/min was significantly lower compared to the pretreatment value of 118 +/- 7 ml/min, but returned three months later to 121 +/- 6 ml/min, and to 131 +/- 10 ml/min at the end of the observation period. A separate analysis was performed on three groups of patients treated by ESWL: with acute calculous disease, chronic calculous disease, and chronic calculous with partial stasis. ESWL treatment in children with acute obstruction was associated with an immediate increase in GFR; however, in chronic calculous disease a decrease in GFR was found. A return of GFR to the pretreatment level was observed at the three-month control in these patients. In patients with acute stone obstruction, at 3 and 12 - 67 months after ESWL treatment, GFR of the treated kidney was found to be significantly increased compared to the pretreatment level. In contrast, in children with chronic calculous disease this increase was modest. This study has demonstrated ESWL to be an effective treatment option for urinary calculi management, which can be safely performed in a pediatric population without long-term effects on the growing kidneys.

Acute Disease↗

[Creation of a new vagina using a part of the rectosigmoid colon].

The paper shows the indications, preoperative and intraoperative evaluation as well as the way to make a new vagina. The authors advise to use part of colon sigmoideum to make a new vagina, this vagina is very much like the real one and the function is unlimited. During the operation the shortest possible part of colon sigmoideum should be taken in order to avoid oversecretion (mucorrhoea). After taking the segment and making termino-terminal anastomosis the tunnel should be made between the bladder and rectum and the segment should be stitched to the introitus of the vagina. For three weeks after the operation the patient should keep a tampon in the [figures: see text] new vagina and we suggest the dilatation of the introitus for three months. After the three months period we advise the sexual intercourse. The number of postoperative complications was minimal and the sexual intercourse was normal.

Colon, Sigmoid↗

[Fixation of the vagina and neovagina with the sacrospinal ligament].

In order to fix the prolapse of vaginal vault after vaginal or abdominal hysterectomy we use the technique of transvaginal sacrospinous colpopexy. The authors used this technique for the firs time when they have made neovagina at male transsexual. The technique is as follows: after making the tunnel between the bladder and recrum, under the control of the left hand fingers the vagina, or neovagina is fixed to sacrospinous ligament. No complications or recidive followed the operation ever. The authors point out that the skillfull surgeon should know very well the anatomy of both male or female pelvis in order to perform this operation.

Female↗

Extravesical detrusor tunneling: a variant of antireflux procedure.

Detrusor tunneling procedure is an extravesical technique, which provides antireflux implantation of different tube systems (ureter, appendix, tubularized preputial flap, tapered ileum). The main characteristic of the technique is the formation of extravesical submucosal tunnel by creating a bridge from the unresected bladder muscle under which the tube is passed. During the period from January 1987 to July 1995, the technique was performed on 442 different tube systems: 402 ureters, 12 appendices, 26 tubularized preputial flaps and 2 tapered ileums. Patients were aged from 15 days to 42 years (mean 39 months). Follow-up was from 2 months to 8 years (mean 2.9 years). Postoperative complications occurred in 11 cases. There were 3 stenoses and 5 refluxes in ureteroneocystostomies, and one stenosis and 2 urine leakages in continent cutaneous vesicostomies. The extravesical detrusor tunneling procedure could be a very useful method for antireflux implantation of various tube systems.

Adolescent↗

[Surgical treatment of vesicoureteral reflux by tunnelling of the detrusor muscles].

Detrusor tunnelling is an extravesical surgical procedure of ureteral reimplantation. It is surely the least traumatic method of surgical correction of vesico-ureteral reflux because antireflux mechanism is achieved with minimal detrusor muscle dissection. This procedure simplifies implantation of dilated ureters, double ureters as well as the ureters shortened by previous antireflux surgical procedures. Ureteral tapering is unnecessary. One hundred and forty detrusor tunnelling uretero-cysto-neostomies in 102 patients have been performed in the University Children's Hospital between January 1990 and September 1994. The youngest patient was 1 month old and the eldest was 15 years (mean age 6.8 years). Indications for surgical treatment were primary (45.0%) and secondary (26.4%) megaureter as well as grade IV & V (international classification) vesico-ureteral reflux (28.6%). Follow up was 1-40 months (mean 26 months). Excellent postoperative results were achieved in 130 detrusor tunnelling uretero-cysto-neostomies, i.e. more than 90% of patients. Complication rate was 7.1% (6 patients-10 ureteral units) and about one third were classified as major-postoperative relapses or stenosis or minor-intraoperative mucosal perforation, hematuria, parahiatal diverticulum, spontaneous proximal migration of ureteral double J stent-about two thirds.

Adolescent↗

[Ultrasonographic findings of upper urinary tract dilatation after the subureteral teflon injection (STING) anti-reflux procedure in children].

A review of ultrasonographic urotract controls was done in 487 children (390 female and 97 male) in whom subureteral Teflon paste had been endoscopically infected in order to avoid vesicoureteral reflux. Dilatation of the upper urinary tract was visualized in 91 of 732 ureters (12.43%). Upper urotract dilatation may be either a sign of the obstruction of ureterovesical junction caused by Teflon or recurrence of vesicoureteral reflux. Echosonographically, 4 types of dilatation were disclosed, each having, a particular diagnostic or therapeutic approach. Acute dilatations associated with pain (2 patients-0.4%) were subjected to emergency surgery (ureterocystoneostomy). Chronic dilatation, which did not abate even after 4 weeks (6 ureters-0.81%) was identically treated. A temporary dilatation usually withdrew spontaneously after 1-2 weeks (66 ureters-9.01%). Patients with delayed occurrence of intermittent dilatation (17 ureters-2.32%) underwent control micturating cystosonography for suspected reflux recurrence.

Adolescent↗

Our modification of onlay island flap urethroplasty in severe hypospadias.

A variant of the only island flap urethroplasty in severe hypospadias repair is described. The principles of technique are: mobilizing of urethral plate, without dividing it, in order to release chordee; creation of pedicle island flap on the dorsal penile skin, with redundant vascularized tissue, which is transposed to the ventral side of penis by buttonhole maneuver; the flap is onlayed to the mobilized urethral plate, while all suture lines are covered with a very wide pedicle of flap, which is decisive for the successful outcome of the operation. During the last 3.5 years (1990-June 1993) the technique was applied in 124 cases of severe hypospadias, aged 12 months to 19 years, with lower complication rate (stricture, fistulas, diverticulum) in comparison to island flap tubularizing urethroplasty (5-15% of patients).

Adolescent↗

Phalloplasty in children and adolescents using the extended pedicle island groin flap.

An operative procedure for phalloplasty is reported that uses an extended pedicle island groin flap. Forming a combined groin and lower abdominal flap based on the superficial iliac and epigastric vessels is the main characteristic of this technique. The flap consists of 3 parts: 1) the lateral narrow hairless part for the neourethra, 2) the medial wide part for neophallus shaft reconstruction and 3) the base of the flap on which a flap pedicle is formed and lengthened by de-epithelializing the skin. The pedicle includes subcutaneous tissue with blood and lymph vessels. The neourethra and neophallus shaft are reconstructed using a tube-within-tube technique. The size of the flap depends on patient build. The flap is transferred to the recipient area, that is to the level of the lower margin of symphysis. Anastomosis of the new and native urethra may be done simultaneously or during the second stage of the procedure. The donor site skin defect is closed by direct approximation. During 3 years (1991 to 1993) this flap technique was performed on 24 patients (age 12 to 18 years). There were 2 main indications for treatment: 1) complete absence of the penis, and so total reconstruction of the phallus was done and 2) small dimensions of the penis or just a penile stump, and so augmentation of the penis was done. Specific indications were female transsexualism in 4 patients, penile amputation in 2 and a small disabled penis in 18 (the exstrophy-epispadias complex, intersex and micropenis). Followup ranged from 6 to 42 months (average 29). A new phallus of satisfactory dimensions was achieved in all cases. Complications included partial necrosis of the flap in 2 patients, fistulas in 2 and stenosis of the urethral anastomosis in 1. These complications were successfully resolved by corrective surgery. The method is simple and timesaving with a minor complication rate. This technique is the available alternative to the most commonly used procedure, that is microsurgical free tissue phalloplasty.

Adolescent↗

Onlay island flap urethroplasty for severe hypospadias: a variant of the technique.

A variant of the onlay island flap urethroplasty in severe hypospadias repair is described. The principles of the technique include mobilization of the urethral plate without dividing it, release of chordee, creation of a pedicle island flap on the dorsal penile skin with redundant vascularized tissue that is transposed to the ventral side of the penis by a buttonhole maneuver, and onlay of the flap to the mobilized urethral plate, covering all suture lines with a wide pedicle of flap. During the last 3 years this operation was performed in 92 patients 12 months to 19 years old with severe hypospadias. The complication rate was 5%.

Adolescent↗

Laparoscopy in the diagnosis of non-palpable testes.

OBJECTIVE: To determine whether laparoscopy is a reliable method for the diagnosis of non-palpable testes. PATIENTS AND METHODS: From January 1991 to February 1993 laparoscopy was performed in 126 patients, aged 6 months to 29 years (mean 5.2 years), with non-palpable testes. Of these, 98 had unilateral and 16 bilateral non-palpable testis, and 12 had previously undergone corrective surgery. Within the same period, 1163 patients underwent surgery for undescended testes. RESULTS: In the group of 126 patients, 146 testes were searched for. The testes were laparoscopically diagnosed in 70 instances (48%). Of these, 46 were unilateral, 18 bilateral, and six testes were in children who had previously undergone surgery. Non-palpable testes were predominantly on the left side. All testes located were situated between the external iliac vessels and the internal inguinal ring or within the inguinal ring. Of the 146 testes searched for, 76 (52%) were absent. CONCLUSION: Laparoscopy is the most satisfactory method for the diagnosis of non-palpable testes, when carried out by an experienced endoscopist.

Adolescent↗

Pharmacokinetics of an immunomodulator peptidoglycan monomer in mice after intravenous administration.

A 14C labeled low molecular weight immunomodulator, peptidoglycan monomer (14C-PGM), was injected intravenously (i.v.) into mice. At various time intervals thereafter (15 min-6 h), radioactivity in the urine, whole blood, plasma, kidneys, liver, spleen, lungs, intestines and the brain of the mice was determined. Shortly after injection, 14C-PGM was very rapidly excreted from the organism, so that 1 h following administration, 80% of the radioactivity was found in the urine (62% as unchanged PGM and the rest as the metabolites pentapeptide and disaccharide). At the same time, around 2% of the injected material was found in the blood. Six hours after injection, equal quantities were found in the intestines, liver and blood (0.5%), slightly less in the kidneys, lungs and spleen (0.2-0.3%) and the least quantity in the brain (0.04%). However, the dynamics of retention in the organs was evidently different. In the kidneys, lungs and spleen, radioactivity steadily decreased over the studied period. In the liver following an initial decrease, radioactivity remained the same 3 and 6 h after injection. On the other hand, in the intestines and brain PGM seemed to accumulate rather than disappear following i.v. administration. This fact should be considered when explaining different biological activities of low molecular weight bacterial peptidoglycans.

Acetylmuramyl-Alanyl-Isoglutamine↗

Penoscrotal transposition with hypospadias: 1-stage repair.

A 1-stage surgical repair of penoscrotal transposition with hypospadias is described. The basic principles are correction of hypospadias with the best vascularized island penile skin flap used for a new urethra and 2 vascularized sliding skin flaps used for reconstruction of the penile skin, and transposition of the penis to the suprascrotal position in the area of the mons pubis, with mobilization plus midline testicular fixation (inter-orchiopexy) and scrotoplasty. This technique was applied in 42 patients 2 to 9 years old between 1986 and 1991. The complications were 2 urethral stenoses on the proximal anastomosis (1 was treated successfully by urethrotomy and 1 by an open operation) and 2 fistulas (successfully treated by surgery), while 2 patients required additional correction of penoscrotal transposition.

Child↗

Epispadias surgery--Belgrade experience.

From 1987 to 1991, 46 patients underwent surgical treatment for epispadias. Of these, 14 had isolated epispadias and 22 had epispadias within the exstrophy/epispadias complex. The patients ranged in age from 6 months to 20 years. To correct the genital aspect of the anomaly the basic principles of Ransley's technique were used. In addition, the island flap technique was used for the most severe, so-called "cripple" form. In patients with exstrophy/epispadias complex, only elongation of the penis was performed during primary reconstruction, while the correction of epispadias, using the above techniques, was performed in the second-stage operation. Complications occurred in 6 patients.

Adolescent↗

Bladder exstrophy and anterior pelvic osteotomy.

Between August 1988 and December 1991, 36 children with bladder exstrophy underwent surgery for primary bladder reconstruction. Each child was either untreated or had already been treated unsuccessfully. The operative technique involved bilateral osteotomy of the superior ramus of the pubic bone. In infants the cartilaginous ischiopubic junction, acting as an articulation, allowed symphyseal approximation, while in older children this was achieved by fracture of the inferior ramus of the pubic bone. The bladder was either closed or, in most cases, the exstrophic bladder plate was inserted deep into the pelvis, allowing subsequent epithelialisation of the bladder and further formation and growth. Follow-up up for 3.5 years showed bladder capacities of 40 to 150 ml. Some patients underwent an additional augmentation enterocystoplasty. Primary bladder reconstruction remained uncompromised in 7 patients who developed moderate (and 1 complete) rediastasis of the pubic bones. All exstrophic bladders are reconstructible, particularly in older children.

Bladder Exstrophy↗

[Rubeola in the population of Subotica 1978-1989].

The circulation of acute rubeola in the population of Subotica was analyzed from 1978 to 1989 regarding general and specific morbidity, the periodicity of occurrence and the cyclic increase in frequency. On the basis of a set clinical diagnosis 11246 cases of rubeola have been registered. Vaccination against rubeola is not conducted in Subotica, therefore this viral contagious disease has an endemoepidemic course. The highest epidemic waves have been registered in 1981 with 2117, and in 1984 with 2662 reported persons. The greatest agglomeration of those affected is in the age group of 5 to 9 years with 4475 (39.79%) of cases. The epidemic waves are divided by two calmer interepidemic periods in 1982 and 1983 as well as in 1986 and 1987. In the population of Subotica the occurrence of acute rubeola is increased at the end of winter with a predomination in the spring months.

Adolescent↗

[Surgery in recurrence of undescended testes].

In the period from Jan. '80 to Dec. '87 at the Pediatric Surgical Clinic in Belgrade 119 patients were operated upon or 147 recurrencies of undescended testes; in 28 cases (23.52%) there were bilateral recurrences. 4 patients were twice unsuccessfully operated on at the same side. The authors analyse the causes of failures of orchiopexy; the proved mistakes were divided into four groups: a) Mistakes due to the undiscovering of the testis, b) unpreparation, or insufficiently preparated the testis from surrounding tissues, c) insufficiently shortening of the testis' way toward the scrotum, and d) mistakes being occasionally arised during the fixation of the testis into the scrotum. During the first unsuccessful operation 20 testes have atrophied, so that a reintervention consisted only in the exploration. In other cases the testis was placed into the scrotum regardless whether it was normal or hypotrophic. In two cases a Fowler-Stephens procedure was carried out, and in one case an autotransplantation of the testis was done. An improvement was found in 89 testes (60.57%), while 38 cases (25.85%) remained with the same characteristics, as they were in the course of our surgical interventions.

Adolescent↗