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Biomedical subjects

S Perry

Publications and source records attributed to S Perry.

17 recordsLinked to original sources
PubMed1979

NIH panels analyze issues on technology.

Experts at NIH's "consensus development" technology assessment conferences study a wide range of issues and make recommendations to help guide users of medical technologies.

Congresses as Topic↗
PubMed1978

Quantitative description of cell cycle kinetics under chemotherapy utilizing flow cytometry.

A discrete time cell cycle kinetics model is developed to account for the effects of cytotoxic chemotherapy, particularly including the existence of cells destined to die. A model structure is determined from related experiments, leaving key parameter values undetermined. These values are found by determining the best least squares fit of the predicted to the observed DNA distribution data at a series of time intervals. The numerical methods include separable least squares, linear inequality constrained least squares and the Gauss--Newton method. This approach is applied to an experiment in which the Ehrlich ascites tumour was given a single dose of bleomycin. The results include several different parameters, including the age response function and a time series of cell age and DNA distributions, which can be used as a basis for further treatment.

Animals↗
PubMed1977

Preparation of mononuclear cell subpopulations from normal human peripheral blood.

By the use of velocity sedimentation at unit gravity, in combination with methods of cell separation based on differences in density and in surface membrane receptors, it has been possible to obtain concentrates of mononuclear cell subpopulations from normal human peripheral blood. T and non-T lymphocytes have been harvested with a good yield and a high degree of purity. Monocytes may also be efficiently recovered using these procedures.

Basophils↗