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Biomedical subjects

S Pinsky

Publications and source records attributed to S Pinsky.

44 records · Page 3Linked to original sources
PubMed1977

Radionuclide venography: correlation with contrast venography.

Radionuclide venography and contrast venography were performed in 47 limbs of 35 patients, and the findings were compared with respect to their location and characteristics. Positive radionuclide venogram findings were area of decreased radioactivity flow corresponding to the region of thrombosis, abnormal collateral flows, and radioactivity stasis below the lesion. A delayed clearance of radioactivity alone in the calf did not indicate venous thrombosis. The overall concordance between radionuclide venography and contrast venography was 89%. The result indicates that radionuclide venography, while technically simple, is a reliable test for the detection of venous thrombosis in patients with signs and symptoms of deep-vein thrombosis.

Humans↗
PubMed1976

Thyroid scintigram. Sensitivity with sodium pertechnetate Tc 99m and gamma camera with pinhole collimator.

To evaluate the reliability of thyroid scintigraphy in the diagnosis of nodular growth, scintigrams of patients who later underwent thyroidectomy were reviewed and correlated with pathologic findings. The scintigrams were all obtained with a 5-mm single-hole collimator-equipped gamma-scintillation camera after intravenous injection of 5 millicuries of sodium pertechnetate Tc 99m. In the group of 92 patients, six of whom had two histologically different lesions, 149 nodules were identified pathologically. There were 26 nodules 2 to 5 mm in diameter, of which 22 were benign and four were malignant. None of the 22 benign nodules were delineated scintigraphically. Superior image quality and resolution, low radiation dose, technical simplicity, and speed make 99mTc pinhole-camera scintigraphy the best procedure available for routine thyroid imaging.

Adenocarcinoma↗
PubMed1976

Comparison of 99mTc and 123I for thyroid imaging.

Thyroid images were obtained with 99mTc and 123I, using a scintillation camera and pinhole collimator, from 85 patients selected from over 1,000 patients predisposed to the development of thyroid neoplasms by prior radiotherapy. In 66 of 85 patients 99mTc and 123I gave essentially similar information, whereas in 19 patients some thyroid-image disparity was seen. In 11 of these 19, focal areas of increased 99mTc concentration were not seen with 123I. Radioiodide images showed slightly better contrast than the 99mTc images but required a longer imaging time and usually did not provide more information; in a few cases 99mTc showed abnormalities more readily. Regardless of which radionuclide was used, oblique views were needed to define some abnormalities. Currently 123I does not provide significant advantages over 99mTc for routine thyroid imaging. However, 123I is preferred in patients with very poor thyroid function and in those with suspected retrosternal thyroid tissue. In addition, areas of increased 99mTc concentration should also be studied with 123I.

Humans↗
PubMed1975

99mTc-pertechnetate thyroid scintigraphy in patients predisposed to thyroid neoplasms by prior radiotherapy to the head and neck.

Histories, physical examinations and 99mTc-pertechnetate imaging were used to evaluate 1,452 persons who had had x-ray therapy to the neck region for benign conditions 18 to 35 years previously. Thyroid abnormalities were found in 301 patients (21%) and thyroid malignancy was found in 29% of 193 patients with abnormal studies who were explored surgically. Thyroid imaging detected 96% of these abnormalities, 40% of which would not have been unequivocally established by physical examination alone. Nuclear imaging could not distinguish benign from malignant lesions.

Adenocarcinoma↗
PubMed1975

Visualization of nonvascular cranial tumor in cerebral flow study: case report.

Unusual results were obtained from a cerebral blood flow study and a brain scan performed on a patient with an uncommon, nonvascular scalp tumor eventually identified as a proliferating trichilemmal cyst with acanthosis. The tumor accumulated the radionuclide during the early phase of the cerebral flow study, and the increased radioactivity was persistent, being prominently observable in a scan made 3 min and 2 hr after the radionuclide injection. This unusual, positive finding in a cerebral blood flow study of a nonvascular tumor was thought to be a consequence of the higher counting efficiency resulting from the lack of shielding by the skull and from the larger volume of the tumor tissue.

Aged↗