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S Pisa

Publications and source records attributed to S Pisa.

2 recordsLinked to original sources

A 915-MHz antenna for microwave thermal ablation treatment: physical design, computer modeling and experimental measurement.

A 915-MHz antenna design that produces specific absorption rate distributions with preferential power deposition in tissues surrounding and including the distal end of the catheter antenna is described. The design features minimal reflected microwave current from the antenna flowing up the transmission line. This cap-choke antenna consists of an annular cap and a coaxial choke which matches the antenna to the coaxial transmission line. The design minimizes heating of the coaxial cable and its performance is not affected by the depth of insertion of the antenna into tissue. The paper provides a comparison of results obtained from computer modeling and experimental measurements made in tissue equivalent phantom materials. There is excellent agreement between numerical modeling and experimental measurement. The cap-choke, matched-dipole type antenna is suitable for intracavitary microwave thermal ablation therapy.

Computer Simulation↗

A generalized ionic model of the neuronal membrane electrical activity.

A new ionic model of the neuronal-membrane electrical activity has been developed. The proposed model generalizes those usually quoted in the literature, taking into account the significant ionic currents, the temperature dependence of the electrical parameters, and the stochastic synaptic inputs. The model allows us to simulate both the membrane firing activity, as a function of the temperature, and the membrane resistance behavior, as a function of temperature and of intracellular calcium concentration. The I-V nonlinear characteristic, together with histograms and correlograms of the time intervals between spikes, have been numerically reproduced. Various comparisons we have carried out with available experimental data show a good theoretical-experimental agreement.

Calcium↗