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Biomedical subjects

S Pitlik

Publications and source records attributed to S Pitlik.

17 recordsLinked to original sources
PubMed1990

Oral ciprofloxacin treatment of Pseudomonas aeruginosa osteomyelitis.

Twenty-two adult patients with osteomyelitis due to Pseudomonas aeruginosa were enrolled in an open, prospective cooperative study to determine the efficacy of oral ciprofloxacin therapy in a dosage of 750 mg twice a day. Twenty patients received a complete course of treatment and could be assessed for efficacy. There were 12 men and 8 women, with a mean age of 55 years. Six patients had undergone previous, unsuccessful attempts at therapy. Eight patients had clinically important underlying conditions. The most common sites of infection were the sternum (six patients), hip (four patients), vertebrae (four patients), and tibia (two patients). Initial surgical debridement was performed in 18 of the 20 assessable patients. The mean duration of treatment was 2.85 months (range, 1 to 4 months), and that of the follow-up was 27 months (range, 6 to 52 months). Cure was achieved in 19 of the 20 (95%) patients. The only significant adverse effect (which prompted discontinuation of therapy) was severe nausea in one case. Oral ciprofloxacin coupled with adequate debridement is an effective, convenient, and safe therapy in patients with acute and subacute P. aeruginosa osteomyelitis.

Adolescent↗
PubMed1977

Mural endocarditis associated with recurrent false aneurysm of the left ventricle.

Acute bacterial endocarditis developed in a 65-year-old man two years after surgical resection of a false aneurysm of the left ventricle. The patient had cerebral embolic manifestations, and coagulase-positive Staphylococcus aureus was cultured from each of six blood samples. A pericardial friction rub and a changing pansystolic murmur appeared during the third week of hospitalization. The presence of a false aneurysm was once again demonstrated on ventriculographic studies. This was successfully repaired, employing cardiopulmonary bypass. The sequence of events in this patient suggests that bacterial endocarditis at the site of a previous cardiomyotomy might have led to the development of the second pseudo-aneurysm.

Aged↗
PubMed1977

Portal hypertension and esophageal varices in hemangiomatosis of the spleen.

Bleeding esophageal varices and severe portal hypertension developed in a patient with capillary hemangiomatosis of the spleen. No signs of cirrhosis were found at postmortem examination, and preoperative celiac angiography suggested an intrasplenic shunt as the cause of the high portal pressure. Although a very rare condition, this possibility should be considered in the differential diagnosis of esophageal varices.

Arteriovenous Fistula↗
PubMed1975

Fatal undiagnosed tuberculosis in hospitalized patients.

Thirty-seven cases of active tuberculosis were misdiagnosed in Chaim Sheba Medical Center in the years 1964-1974. The diagnosis was made only after death. Twenty-one patients were over 60 years of age. Eleven had hematological disorders, and 12 received steroids (sometimes with immunosuppressive or cytotoxic drugs). Misdiagnosis of miliary tuberculosis is a growing problem and demands special attention. The postmortem examination must be systematic and must include bacteriological and histological studies for establishment of the correct diagnosis.

Adolescent↗