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Biomedical subjects

S Pitrová

Publications and source records attributed to S Pitrová.

12 recordsLinked to original sources

[The first stage of clinical trials of hydrogel lenses manufactured in Czechoslovakia].

The authors give an account of the results of the first stage of clinical trials of Czechoslovak disc-shaped hydrogel lenses made from the copolymer HEMA and methacrylic acid. Hitherto assembled experience provided evidence that the envelope technique for opening of the anterior capsule does not ensure sufficient stability of these lenses in the later stage and their decentration may cause serious complications. Therefore the optimal solution is to place the implant in the capsule after circular capsulorhexy. Improvement of the geometrical and optic properties of the lenses during the subsequent follow-up and their perfect harmony with the surgical technique will produce even better functional results in operated patients.

Aged

[The clinical picture of Fuch's heterochromic cyclitis].

The authors are presenting their experience with the diagnosis and treatment of Fuchs' heterochromic cyclitis. They followed-up 13 patients with this disease for 0.5-3 years. Most often the patients were sent to the clinic with the diagnosis of recurrent anterior uveitis not responding to the treatment with corticosteroids and mydriatics. Patients underwent numerous investigations including neurological, internal and rheumatological examinations. Antibodies against EBV, HSV and CMV were detected. The examination of humoral immunity and HLA was done. The authors describe the ophthalmological findings, the course of the disease and the treatment. They did not find any correlation in the laboratory investigations and the course of the disease, the diagnosis is based on the clinical picture. They point out the advantage of the small incision in the extracapsular extraction of cataract in these patients.

Adult

[Significance of immunologic reactions on the surface of intraocular lenses].

The authors summarize their experience assembled during specular examinations of immunological processes on the surface of the intraocular lens. They describe the incidence of significant components of the immunological reaction--of "large cells", "fibroblast-like cells", round elements, fibrous and acellular membranes on the surface of the intraocular lens. The "large cells" are considered the most important components of the reaction from the clinical aspects. Their incidence depends most frequently on a change in the position of the intraocular lens and non-adherence to therapy in the early postoperative stage. The authors present findings assembled in patients with late changes of the position and formation of synechiae and subluxation, most probably traumatic, and occur in patients who did not respect local corticoid treatment in the early postoperative period. A similar character of the specular finding indicates uniformity of the non-specific reaction which is potentiated by interference with the haemotoocular barrier for various reasons.

Female

[Panophthalmitis as a nosocomial infection].

The submitted paper deals with an epidemic of severe postoperative panophthalmitis, its development, course, causes and sequelae incl. epidemiological characteristics. The disease developed in four patients 40 hours after operation of cataract. Despite treatment all four patients developed septicaemia and therefore the affected eyeballs were eviscerated. From smears of the conjunctival sac of the affected patients and from the contents of the eviscerated eyeball Proteus mirabilis and Enterobacter cloaceae were cultivated. The authors draw attention to the epidemiological association with the eye lotion BSS which was used from which Proteus mirabilis and E. coli were cultivated and with the Ringer solution from which Enterobacter cloaceae and Klebsiella pneumoniae were cultivated. An epidemiological analysis of the epidemic was made and provisions were defined to rule out its recurrence.

Cataract Extraction

[Biocompatibility of retropupillary intraocular lenses].

The authors give an account on the incidence of two types of reactions in the early postoperative period (within two weeks) after implantation of retropupilar intraocular lenses. In a group of 320 patients they observed them in 51 (16%) incl. 17 diabetics. In the group of diabetic patients the incidence of reactions was twice as frequent. A typical fibrin reaction starting on the third day after operation was recorded in 18 patients (5%), in the remaining 33 patients (11%) there was increased opalescence of the aqueous humour, and exudation of cels and cellular structures to the lens surface was associated with the surgical trauma, in particular in beginner implantologists. The two mentioned types of reactions do not have a substantial influence on the final functional effect.

Biocompatible Materials

[Laser microsurgery in glaucoma].

Based on ten years work, the authors summarize their experience with the use of different types of lasers and laser methods in the treatment of glaucomas. They draw attention to the limits of effectiveness of laser microsurgery, to different modifications of hitherto used methods and their combinations. The authors try to define the position of lasers in the therapy of glaucomas.

Glaucoma

Cystinosis with crystal-induced synovitis and arthropathy.

A clinically and experimentally verified intermediary form of cystinosis is described. A 30-year old patient has been examined initially for eye complications confined to the frontal segment of the eye on the cornea and conjunctiva. The joint disease received no attention despite the fact that the motor apparatus of the patient was involved from her childhood. As regards the arthrology, the disease can be classed among crystal-induced synovitis and arthropathy. The lesion of the tubular apparatus of the kidney, which cannot transform vitamin D into its active form, represents an important factor in the genesis of osteoporosis. A description of the intermediary from of cystinosis with eye, kidney and joint symptoms was not found in the literature.

Adult