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Biomedical subjects

S Plontke

Publications and source records attributed to S Plontke.

10 recordsLinked to original sources
PubMed2002

[Recovery of hearing: results of delayed medical treatment in patients with idiopathic sudden hearing loss].

For the treatment of idiopathic sudden sensorineural hearing loss (ISSNHL), a variety of studies about intravenous drug administration with the beginning of treatment in the early period of less then one week after the onset of hearing loss have been performed. In contrast, very little information is available about the efficacy of intravenous drug therapy for ISSNHL with the beginning of treatment later than four weeks after the onset of hearing loss. In a retrospective chart review we studied the treatment results of 57 patients with ISSNHL with beginning of treatment later than four weeks after the onset of hearing loss with no spontaneous recovery of hearing. Patients received a treatment with intravenous administration of Dextran (concentration 40 g/l with NaCl 0.9%) and Procain-HCl (a derivative of the local anaesthetic lidocaine,400-800 mg in a 500 ml rheologic infusion of Dextran 40). 25% of the patients showed a significant improvement of 10 dB or more in hearing threshold at 1000 Hz measured in bone-conducted pure tone audiometry. In a subjective evaluation 53% of the patients noticed a subjective improvement of their individual hearing thresholds.

Adolescent↗
PubMed2002

[Massive Gorham-Stout osteolysis of the temporal bone and the craniocervical transition].

Massive osteolysis Gorham-Stout is a rare, benign but locally aggressive angiomatosis which results in destruction and resorption of bone. The etiology and pathogenesis are undefined. The occurrence of the disease in the skull base is uncommon. A 54-year-old female presented with isolated, one-sided surditas. Eight years before the patient underwent surgery and radiation therapy for treatment of hypopharyngeal cancer. A transtemporal biopsy was taken and a highly vascularized, cystic lesion with destruction of the right occipital and temporal bone and the atlas was found. Histopathology showed thin-walled capillaries with flattened endothelial lining cells. After exclusion of malignant and infectious components the diagnosis of Gorham's disease was established. Review of the literature suggests radiation therapy as the method of choice for stopping the disease's progress. The aim of this case report is to emphasize the Gorham-Stout-Syndrome as a rare differential diagnosis for skull base lesions.

Angiomatosis↗
PubMed2001

Correlation of nasal morphology and respiratory function.

In order to investigate the fluid dynamic preconditions that guarantee a sufficient contact of air with nasal mucosa, we studied flow patterns in modified "Mink's boxes" and in nasal models. As a result, the nose can be divided into 1) a functional area, i.e. area of turbinates, 2) an inflow area, i.e. vestibulum, isthmus and anterior cavum and 3) an outflow area, i.e. posterior cavum, choanae and epipharynx. The vestibulum is shaped like and acts as a bend, redirecting air to the cavum, and as a nozzle, reducing turbulence. With its concavely curved shape, the isthmus facilitates equal distribution of air throughout the entire area of the turbinates. The anterior cavum acts as a diffuser, where turbulence increases and velocity decreases. In the slit-like space of the area of turbinates, the flow behavior is determined by flow dynamics in the inflow area. The structure elements of the outflow area are similar to those of the inflow area but lined up in an inverse order.

Humans↗