[Acute retinal necrosis. Apropos of 2 cases].
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Biomedical subjects
Publications and source records attributed to S Pohl.
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Seventy eight patients with chronic lung diseases were once or repeatedly vaccinated against influenza with a bivalent inactivated vaccine. The vaccination was well tolerated. Systemic reactions and transitory deterioration of the lung disease were exceptional. Fourfold rise of antibodies occurred in 1/3 (H1N1) and 1/2 (H3N2) of the patients. After one year, this increase was no more demonstrable. Annual revaccination is recommended.
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Symptoms and blood glucose levels were recorded by 23 insulin-dependent diabetics during three separate intervals. Each interval spanned 7-10 days, involving 40 symptom-blood glucose recordings. Each symptom's ratings were correlated with their respective blood glucose recording to yield a separate symptom-blood glucose correlation for each interval. These separate symptom-blood glucose relationships were themselves correlated across the three intervals to assess the temporal stability of the symptom-blood glucose relationships. Reliability was found to be variable. Possible explanations for this variability are discussed.
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This case report describes the clinical history of a patient on dialysis, who suffered from a lesion of the brachial plexus, secondary to a mechanical damage after attempted suicide. Therapy with transcutaneous electrical nerve stimulation (TENS) revealed both sufficient analgesia and a striking improvement of the functional situation. Possible causes of the therapeutic success are discussed. The analgesia of TENS therapy, which has almost no side-effects, with the secondarily improved psychic situation, is regarded as the major responsible factor. This method appears to be a rewarding alternative in the treatment of pain syndromes secondary to peripheral nerve lesions.
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Thirty hospitalized diabetics completed symptom checklists immediately prior to monitoring their own blood glucose level seven times a day for 6--10 days. For each subject, simple correlations were computed between each of the physical symptoms and blood glucose level. Most subjects evidenced several symptoms that were highly correlated with glucose fluctuations. Further, the symptoms that were related to glucose differed from subject to subject. The symptom-glucose correlations were reliable and unrelated to sex, age, duration of diabetes, and other individual difference variables. The findings point to a technique wherein patients can learn to perceive physical sensations indicative of changes in blood glucose in natural settings.
The phylogenetic relationships among strains of Pasteurella multocida representing Carter's serogroups A, B, (C), D and E, the type strain (which also represents serogroup A, and biovar 4), the indole-negative strain Schütze HS, and two "dog-type" strains (biovar 6) were investigated by DNA:DNA hybridization using the optical method. The genome DNAs of the "dog-type" strains were almost identical; they displayed, however, only 20% binding with the DNA of the type strain of P. multocida, and even lower or no measurable binding with the DNAs of the other strains tested. The taxon hitherto classified as biovar 6 of P. multocida is therefore considered as a distinct species; yet the data so far available do not rule out that it belongs to a genus other than Pasteurella sensu stricto. - The remaining strains exhibited high genome DNA relatedness, with between 64 and 98% DNA binding. The present data do not rule out the existence of molecular subspecies in P. multocida.
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Clostridium La 1 obtained from a Clostridium kluyveri culture was compared with a typical C. kluyvery strain (DSM 555). The former grows on cortonate and is unable to use ethanol-acetate as carbon sources. The latter grows on crotonate only after long adaptation periods. Resting cells of both strains show also pronounced differences in the fermentation of crotonate. This holds even for C. kluyveri grown on crotonate. Besides several other differences the most striking is that there is no hybridization between the DNA of both strains. Crotonate seems not to be a very special carbon source since C. butyricum and C. pasteurianum grow on crotonate medium supplemented by peptone and yeast extract.
As the base composition of deoxyribonucleic acid has become a highly significant parameter in the taxonomy of bacteria, a reference list for the known deoxyribonucleic acid base composition (G + C) values of bacteria is given which compiles the data published between 1972 and 1978.
In a comparative study, 63 collection cultures representing 38 nomenspecies of, or assigned to, the genera Actinobacillus, Haemophilus, or Pasteurella were characterized by phenotypical features and deoxyribonucleic acid base composition. The latter was calculated from the thermal denaturation point. Biochemical reactions were tested in differential media commonly used for Enterobacteriaceae, and two test procedures were compared: (i) pure cultures with haematin and nicotine adenine dinucleotide added, where necessary, and (ii) xenocultures with an asaccharolytic Acinetobacter strain (ST 661/60). Furthermore, the respiratory quinones, and the effect of fumarate on oxygen-limited growth were considered. On the basis of these and some additional physiological and morphological criteria, a definition of the Actinobacillus-Haemophilus-Pasteurella group as a whole was established which appears to rank as a family. Several misclassified species, i.e. the so-called Actinobacillus actinoides, Haemophilus piscium, Haemophilus vaginalis, Pasteurella anatipestifer, and the organisms of the Bovine Lymphangitis group were eliminated, and the position of so-called Pasteurella piscicida was questioned. Some principles of subdivision of the group, and some of the practical identification procedures were discussed.
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The smoking habits and the lung function of 369 boys and 340 girls aged 6-16 were examined in a school. The boys are beginning to smoke at the age of 9, the girls at the age of 13. 62 per cent of the children aged 16 are smoking (20 per cent of the girls and 30 per cent of the boys are smoking regularely more than 1 cigarette/day). 58 per cent of the children have a smoker in their family. Only 10 per cent of the parents have knowledge about the smoking of their child aged 12, and 59 per cent of the parents of their child aged 16. The lung function tests (ventilation, distribution, bodyplethysmography, single-breath-test, blood gases) of the healthy teen-agers dont show differences between smokers and non-smokers.
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