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Biomedical subjects

S Polansky

Publications and source records attributed to S Polansky.

10 recordsLinked to original sources
PubMed1987

Effect of heparin infusates in umbilical arterial catheters on frequency of thrombotic complications.

We studied 111 infants requiring an umbilical artery catheter, 59 with heparin and 52 without. Thirty-four thrombi were detected, 16 in the heparin group and 18 in the control group. The numbers of thrombi in the two groups was not significantly different, but the number of clotted or nonfunctioning umbilical artery catheters was greater in the control group (P less than 0.05), as was the incidence of hypertension (P less than 0.05). There were no other significant differences between the two groups. We conclude that the use of low doses of heparin may not change the incidence of umbilical artery catheter-related thrombi, but it does appear to lower the incidence of their sequelae.

Aorta, Abdominal↗
PubMed1987

Combined use of alpha-fetoprotein and ultrasound in the prenatal diagnosis of arteriovenous fistula in the brain.

A case of arteriovenous fistula in the brain detected by the combined use of maternal serum alpha-fetoprotein (AFP) and ultrasound in the third trimester of pregnancy is described. The maternal serum AFP concentration at 34 weeks of gestation was 300 ng/mL (2.3 times the median). Stage II diagnostic ultrasonography at 37 weeks revealed a large midline cystic mass, contiguous to a normal-appearing lateral ventricle and surrounded by an abnormal heterogeneous zone of increased echogenicity. At birth, the cord blood AFP concentration was 2 SD above the mean. Subsequent histopathologic examination revealed a vein of Galen aneurysm and fistula in the brain.

Adult↗
PubMed1976

Pregnancy associated with hypergonadotropic hypogonadism.

A case of a 30-year-old female with secondary amenorrhea and relative hypergonadotropic hypogonadism is presented. The patient demonstrated persistently elevated levels of gonadotropins in spite of clinical and laboratory evidence of estrogen production. Laparoscopic directed biopsy revealed a total absence of ova, but in spite of this finding, conception ensued. Variations in ovarian sensitivity throughout the female reproductive period and in certain pathologic states are discussed, as well as the apparent limitation of single laparoscopic directed biopsies for confirming the diagnosis of premature menopause. Finally, the theoretical use of exogenous estrogen to induce ovulation in patients with the ovarian insensitivity syndrome is discussed.

Adult↗
PubMed1976

The effect of L-dopa and clomiphene citrate on peripheral plasma levels of luteinizing hormone-releasing factor.

Response of luteinizing hormone-releasing factor (LRF) and gonadotropin levels to orally administered L-dopa and clomiphene citrate were measured in 13 healthy female volunteers. Testing was carried out during the early follicular phase of the menstrual cycle. The results indicated a suggestive but statistically nonsignificant elevation of peripheral plasma LRF following L-dopa administration but no response following clomiphene ingestion. No acute increase in gonadotropin levels was demonstrated in either group. A low but statistically significant positive correlation was found between luteinizing hormone and LRF values determined from the same samples.

Administration, Oral↗
PubMed1975

Luteinizing hormone, adrenal androgenesis, and polycystic ovarian disease.

Seven oophorectomized patients were administered a total of 60,000 units of human chorionic gonadotropin over a 3-day period, and plasma testosterone levels were obtained. One of the 7 patients demonstrated a definitive response to the hormone but repeat testing proved to be negative. The potential role of luteinizing hormone in the pathogenesis of polycystic ovarian syndrome is discussed and current evidence linking LH to adrenal androgenesis is reviewed. Modifications that may be employed for future study are suggested.

17-Ketosteroids↗
PubMed1975

Virilization associated with bilateral luteomas of pregnancy.

A case of maternal virilization associated with bilateral luteomas of pregnancy is described. Urinary 17-ketosteroids and plasma testosterone fell from markedly abnormal values to normal limits within 2 weeks of delivery. However, symptoms of virilization persisted in the postpartum state. A possible relation between polycystic ovarian syndrome in the nonpregnant state and luteoma of pregnancy is proposed.

17-Hydroxycorticosteroids↗