PubMed Health⌕ Search

Biomedical subjects

S Poleksic

Publications and source records attributed to S Poleksic.

6 recordsLinked to original sources
PubMed1986

Needle aspiration biopsy as an adjunct to mediastinoscopy.

Conventional mediastinoscopy has a small but definite morbidity and mortality. Our continuing study was done to determine whether needle aspiration during mediastinoscopy is a safe and reliable procedure. In 14 consecutive patients having mediastinoscopy, needle aspiration biopsy was also done. There was a 100% correlation between diagnosis made by needle cytology and the final diagnosis, with neither false-positive nor false-negative results. This correlation was only 75% in the forceps biopsy group. In 90% of the cases, the cytopathologist correctly identified the final cell type. There were no complications, even in cases of superior vena caval (SVC) obstructions. The distinct advantages of the technique include high specificity, better tissue sampling, immediate availability of results, reduced morbidity, expanded indications in SVC syndromes, and higher yield than conventional punch biopsies.

Adenocarcinoma↗
PubMed1978

Rapid development of keratoacanthoma and accelerated transformation into squamous cell carcinoma of the skin: a mutagenic effect of polychemotherapy in a patient with Hodgkin's disease?

A 59-year-old white man developed keratoacanthoma of the nose immediately following one course of MOPP polychemotherapy for clinical state IV B mixed cellularity Hodgkin's disease. Despite the dramatic response of Hodgkin's disease to intensive chemotherapy, the skin lesion was rapidly transformed into squamous cell carcinoma in 10 weeks. The immunosuppressive effect of intensive polychemotherapy may play a significant role in accelerating the malignant transformation. We report here our results concerning this complication which may occur in any patient with Hodgkin's disease undergoing intensive therapy.

Antineoplastic Agents↗
PubMed1978

Prognostic value of vascular invasion in squamous cell carcinoma of the head and neck.

Vascular invasion by malignant cells has been an accepted secondary diagnostic or prognostic factor in malignancies of the thyroid and kidney. This study of the initial biopsies from 80 patients with squamous cell carcinoma of the head and neck indicates that penetration of the vascular channels by the tumor is a reliable indicator of the tumor's aggressive character. If discovered in the initial biopsy, this may be a reason to plan more comprehensive and intensive treatment than would be indicated by the clinical stage alone.

Adult↗
PubMed1976

Benign atypical fibroxanthoma or a malignant tumor? A warning. Case reports.

Atypical fibroxanthoma of the skin has been recognized recently as a pseudo-malignant tumor, probably reactive in nature. By all the classic morphological criteria, the lesion appears to be malignant--but in behavior it is benign. In older patients the head and neck are primarily involved, while in younger patients these tumors appear on the covered areas of the trunk and limbs. Complete local excision is considered to be adequate treatment.

Fibroma↗