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Biomedical subjects

S Pollard

Publications and source records attributed to S Pollard.

22 records · Page 2Linked to original sources

Developmental changes in the mother-child interactions of hyperactive boys: effects of two dose levels of Ritalin.

The mother-child interactions of 60 hyperactive children subdivided equally into five age levels (years 5, 6, 7, 8 and 9) were studied during free play and task periods in a double-blind drug-placebo evaluation of two dose levels of Ritalin (0.3 and 0.7 mg/kg bid.) on these interactions. No effects for age or drug condition were found during free play. In contrast, age effects were significant in the task period with the children increasing their compliance and sustained attention with age. In response, mothers decreased their direction and control while increasing their passive observation of the children. Several drug effects were found during the task period, indicating that only the high dose of Ritalin produced improvements in child compliance. However, both doses resulted in decreases in mothers' controlling reactions to the child's compliance and off-task behavior as well as in ratings of home behavior problems. Drug effects were essentially the same across all five age levels. The interaction patterns of hyperactive children are similar to those found in younger normal children in previous research, apparently reflecting a chronic lag in this pattern in hyperactive children that may be improved with stimulant medication.

Adult

The effects of Anemonia sulcata toxin II on vertebrate skeletal muscle.

Some effects of the sea anemone toxin, ATX-II, on vertebrate skeletal muscle have been described. At a concentration of 1 X 10(-7)-1 X 10(-6)M, ATX-II caused a sodium-dependent depolarization of the muscle fibres of the rat soleus and extensor digitorum longus, of the mouse soleus and extensor digitorum longus and of the chicken posterior latissimus dorsi. The muscle fibres of the frog sartorius were insensitive to the toxin. Action potentials generated by direct stimulation were prolonged by ATX-II, but the degree of prolongation was variable. Chicken posterior latissimus dorsi muscle fibres were most sensitive in this regard, and mouse extensor digitorum longus were least sensitive. Both denervated and immature muscle fibres were more sensitive to ATX-II than mature innervated muscle fibres. The sensitivity to ATX-II declined rapidly as muscle fibres matured. In some muscles, the prolongation of the action potential was enhanced by repetitive stimulation, but not by the passive depolarization or hyperpolarization of the muscle fibres. The actions of ATX-II could be reversed by washing in all but the innervated soleus of the mature rat.

Action Potentials

The utilization of a consulting clinical psychologist within an urban vision training clinic.

Multi-disciplinary evaluation of children with learning problems is necessary in many cases. The private optometrist frequently has psychological resources available to him and his patients. In an urban setting with an inner city patient population, the clinical practitioner has much difficulty in referring and in retrieving psychological data. The function of a consulting psychologist as an attending staff member of the Visual Training Department of the Optometric Center of New York is described, and a preliminary report of 52cases referred for psychological consultation between September 1, 1972 and June 30, 1973 is presented.

Community Health Services