PubMedDate not supplied
From 1974 to 1983, 124.471 cervico-vaginal smears after Papanicolaou were analysed. Group I and II findings numbered 97.06%, group III 2.28%, group IV 0.54%, and group V 0.12%. Most findings of groups III and IV related to women in their forties (32%), then to those in the fifties (28.2) and in the thirties (26%). Out of 1522 group III women, 261 were histologically examined: there were 78 dysplasias, 108 carcinomas in situ, 27 invasive carcinomas, and 48 benign changes. Out of 317 group IV women, there were 33 benign changes, 66 dysplasias, 158 carcinomas in situ, and 60 invasive carcinomas. Out of 78 group V women, there were 7 benign changes and dysplasias each, 17 carcinomas in situ, and 47 invasive carcinomas. Most dysplasias and carcinomas in situ were found in women in their forties (39.9), a smaller number in women in their thirties (29.4%), and the smallest number in women in their fifties (22.5%). Out of all invasive carcinomas, the highest number was found in women in their fifties (32.09%), the peak being about ten years later than that relating to dysplasias and carcinomas in situ. The conclusion is that the screening of the uterine cervix should start already at the time of defloration.