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Biomedical subjects

S Pruna

Publications and source records attributed to S Pruna.

7 recordsLinked to original sources
PubMed2002

A networked electronic patient record system for diabetes.

This paper describes the development and clinical implementation of the SincroDiab--a synchronized diabetes register for the routine clinical practice in a LAN and for design of long-term trials and epidemiological studies based on the GEHR (Good European Health Record) architecture. The objectives of the SincroDiab system were to address the need to establish a more efficient and more effective information infrastructure to improve the ability to share patient record information among health care providers, to reduce the health care delivery costs, to meet the requirements of legal, regulatory or accreditation standards, to share comparable patients data among different sites within a multi-entity health care delivery system and to improve quality of care by network connecting the data repository to clinical workstations and departmental systems.

Diabetes Mellitus↗
PubMed2000

The Black Sea Tele-Diab System: development-implementation-clinical evaluation.

This paper describes the application of the GEHR (Good European Health Record) architecture to develop a system to enable the storage and exchange of EHCRs (Electronic Health Care Record) of patients with diabetes, in the Black Sea area. The objectives of the Black Sea Tele Diab System (BSTD) were to develop and evaluate the use of a fully-computerised healthcare record system in a clinical setting, to promote the use of electronic data exchange of healthcare information and to provide a framework for the epidemiological study and monitoring of diabetes care.

Diabetes Mellitus↗
PubMed1990

Peripheral sympathetic neuropathy evaluated by recording the evoked electrodermal response using an impedance reactometer.

Autonomic nervous dysfunction was indirectly evaluated on the basis of the skin electrical resistance relative variation (SERV), recorded by our recently developed system, with two pairs of surface electrodes placed on the palm and on the sole of the foot, after the application to the subject of a sensory stimulus (sound 60 dB, 860 Hz, 0.5 s duration) or in the course of a Valsalva manoeuvre. The results were digitally measured and recorded on thermosensitive millimetric paper analysing the following parameters: latency (LT), i.e. the time interval(s) between application of the stimulus and onset of SERV, both at palm (LTh) and foot (LTf); amplitude of the response (mm) recorded and evaluated in the form of SERV; velocity of the response as rate of time change (Vr) and autonomic conduction velocity, -ACV (m/s), calculated by the height/LT ratio. The present study refers to a group of 60 diabetic patients: 32 F/28 M; mean age +/- SD 46.8 +/- 11.8 years; 29 insulin-dependent, 21 non-insulin-dependent; duration of diabetes 8.6 +/- 4.6 years. The data were compared to those recorded in a group of 50 nondiabetics (22 F/28 M; mean age 47.5 +/- 14.1 years) who were apparently healthy. A significant statistical difference (P less than 0.001) was found between diabetic patients and controls for all studied parameters: LTh (s) 2.65 +/- 1.2 vs. 1.91 +/- 0.6; LTf(s) 3.6 +/- 1.4 vs. 2.6 +/- 0.7; SERV (mm) 7.5 +/- 4.8 vs. 18.5 +/- 6.6; Vr (mm) 4.4 +/- 2.1 vs. 13.5 +/- 5.3; ACT (m/s) 0.41 +/- 0.23 vs. 0.97 +/- 0.18.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1990

Quantitative noninvasive electrophysiological evaluation of the activity of the cutaneous division of the sympathetic nervous system.

The functional status of the cutaneous division of the orthosympathetic nervous system was indirectly and non-invasively assessed by monitoring the skin electrical relative resistance variations (SERV). The advantages of our recording system of second generation were (1) simultaneous recording on two or four channels of the evoked electrodermal response to psychic or to sensorial stimulus; (2) self-balancing system which allows the recording of the relative variation of the electric parameter, i.e. its variation with time; (3) precise determination of the amplitude (omega/s, mu F/s) of the evoked response; (4) reference of the latency time (LT) of the evoked response to the length of the anatomical pathway of the signal giving the autonomic conduction velocity (ACV). Decrease in diabetic autonomic neuropathy of both spontaneous and evoked electrodermal activities suggested their relationship with cutaneous sympathetic activity.

Acoustic Stimulation↗
PubMedDate not supplied

The pattern of the electrodermal activity as indicator of stress related reaction.

The aim of the present study was to characterize the patterns of signals associated with noninvasively detected skin sudomotor transient reflexes in a group of 221 apparently healthy people, aged between 16 and 72 years. By means of two pairs of surface electrodes applied respectively to the palm of the hand and to the sole of the foot skin impedance changes were recorded as two electrodermal parameters: skin electrical resistance and skin electrical capacitance. The recordings were obtained under standard conditions initially in the basal resting state of the subject and then, after the application of some standardized stimuli (evoked electrodermal responses). In terms of the basal (spontaneous) electrodermal activity and the evoked responses the subjects were divided into three categories: I--those with a high threshold of sympathetic activation (quiet basal trace and ample evoked responses); II--those with a medium threshold for sympathetic activation (basal trace with some spontaneous electrodermal activity, but obviously of a lower amplitude than the evoked responses); III--those with a low threshold for sympathetic activation (a tracing showing frequent, larger spontaneous sympathetic discharges from which the evoked responses cannot be distinguished). Of the 221 subjects, 22.2% in group I, 69.2% were included in group II, and 8.6% in group III. Our data show that each individual presents a characteristic electrodermal pattern which expresses the degree of stability/instability of the sympathetic nervous system, the most sensitive component of the physiological stress reaction system.

Adolescent↗