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Biomedical subjects

S R Bussolari

Publications and source records attributed to S R Bussolari.

5 recordsLinked to original sources

The distribution of fluid forces on model arterial endothelium using computational fluid dynamics.

Numerical calculations are used in conjunction with linear perturbation theory to analyze the problem of laminar flow of an incompressible fluid over a wavy surface which approximates a monolayer of vascular endothelial cells. These calculations model flow conditions in an artery very near the vessel wall at any instant in time, providing a description of the velocity field with detail that would be difficult to identify experimentally. The surface pressure and shear stress distributions are qualitatively similar for linear theory and numerical computations. However, the results diverge as the amplitude of surface undulation is increased. The shear stress gradient along the cell model surface is reduced for geometries which correspond to aligned endothelial cells (versus nonaligned geometries).

Arteries

Dual-task performance on an interactive human/computer space shuttle flight experiment.

INTRODUCTION: This paper details ground-based results of the Mental Workload and Performance Experiment (MWPE) which examines human performance for cognitive decision-making and eye-hand-coordinated motor tasks. MWPE is manifest on the International Microgravity Laboratory (IML-1) Space Shuttle Mission and is scheduled to fly in December of 1990. The MWPE protocol combines a Sternberg memory search with a Fitts' target acquisition resulting in a "Fittsberg" dual-task paradigm. The purpose of this study was to evaluate the serial execution theory underlying the Fittsberg dual-task paradigm. METHODS: A total of nineteen subjects performed two experimental test batteries. Unusual body dynamics were imposed on subjects in order to assess altered environment performance. In the first test battery, subjects performed experiments in either the upright postural orientation or the supine (recumbent) postural orientation. During the second test battery, an altered environment was electronically created by introducing a first-order lag characteristic between the graphic input device and the computer. Performance and workload were evaluated by reaction time, movement time, and subjective rating measurements for the dual-task paradigm. RESULTS: The major contributors to reaction and movement times are as predicted by Sternberg and Fitts, however, there are many other influences not accounted for by the classical models. For MWPE, interdependence among the memory set size and index of difficulty experimental variables is in conflict with the serial execution assumption of the Fittsberg dual-task paradigm. CONCLUSIONS: When interaction among variables exists, the dual-task paradigm can not simply be modeled as a Sternberg memory task plus a Fitts target acquisition, rather, new performance metrics for the memory search and target acquisition tasks require that all the significant variables in the MWPE protocol be modeled. The interdependence among variables hints that the operator incorporates some degree of parallel processing rather than exclusively performing in a serial manner.

Humans

Flight simulator platform motion and air transport pilot training.

The influence of flight simulator platform motion on pilot training and performance was examined in two studies utilizing a B-727-200 aircraft simulator. The simulator, located at Ames Research Center, is certified by the FAA for upgrade and transition training in air carrier operations. Subjective ratings and objective performance of experienced B-727 pilots did not reveal any reliable effects of wide variations in platform motion design. Motion platform variations did, however, affect the acquisition of control skill by pilots with no prior heavy aircraft flying experience. The effect was limited to pitch attitude control inputs during the early phase of landing training. Implications for the definition of platform motion requirements in air transport pilot training are discussed.

Adult