Biomedical subjects
Publications and source records attributed to S R Checketts.
Plantar and periungual warts are notoriously difficult to eradicate. Two cases of nongenital warts in teenage girls are presented. Imiquimod was used in combination with cryotherapy for the periungual warts and with occlusion for the plantar warts. Both cases showed complete resolution and that imiquimod may be more effective on thicker keratinized (nongenital) skin when occluded or used in combination with cryotherapy.
Dermatofibrosarcoma protuberans (DFSP) occurs most commonly on the trunk, affects all races, and often develops between the second and fifth decades of life. It is uncommon in childhood and is sometimes mistaken for a vascular lesion, as it often presents as a blue macule or small nodule. Review of the English literature revealed approximately 152 cases of DFSP developing before 16 years of age and only 19 claimed congenital cases. A case of congenital dermatofibrosarcoma protuberans is presented with a literature review and discussion of congenital and childhood presentations of the tumor.
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Drug-induced pseudoporphyria cutanea tarda has been attributed to many different medications including several nonsteroidal anti-inflammatory drugs (NSAIDs). Often the patients taking these anti-inflammatory medications became part of a treatment dilemma when one of the drugs is deemed the cause of a blistering disease. We present a prototypical case of NSAID-induced pseudoporphyria cutanea tarda and suggest alternative NSAIDs that may be safely used in these patients.
Many different drugs and agents have been reported to induce pseudoporphyria. Nonsteroidal antiinflammatory agents have been implicated as some of the most common causes. The first case reports of nabumetone (Relafen) induced pseudoporphyria have recently been published. We report two more cases of pseudoporphyria induced by nabumetone and stress the importance of physician awareness with the use of this drug.
Generalized essential telangiectasia was well defined more than 30 years ago. There have been no reported cases of associated gastrointestinal (GI) bleeding. Recurrent hemorrhage in the setting of telangiectases, including GI bleeding, is more typically associated with hereditary hemorrhagic telangiectasia. We report a unique case of a woman with generalized essential telangiectasia and GI bleeding from a watermelon stomach. We include a brief review of the literature of watermelon stomach, generalized essential telangiectasia, and hereditary hemorrhagic telangiectasia.