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S R Dakin

Publications and source records attributed to S R Dakin.

2 recordsLinked to original sources

Localization of element clusters by the human visual system.

A spatial localization task was used to determine the accuracy of localization of random element clusters about their centroid. The random element clusters were generated within a circular region and the observers' task was to decide whether the cluster lay to the right or left of a reference line, defined by two vertically separated reference elements. Both the reference elements and the cluster elements themselves were comprised of spatially narrowband stimuli (gabor patches), and were presented at a constant suprathreshold level. The thresholds for localization of the element cluster were measured with varying element number, and for a number of different sizes of circular region and element. The relationship between localization threshold and element number was not monotonic. Thresholds were found to rise with increasing element number up to about six elements within a region, and to then fall with further increase in element number. Asymptotic thresholds at high element number were indistinguishable from those obtained for filled circles of the same size. The results do not conform to any one of a number of models based on a centroid analysis alone. By manipulating the spatial and orientational properties of the elements comprising the cluster to be localized it was determined that the more central mechanism underlying localization receive input from different spatial and orientation filters.

Contrast Sensitivity↗

Terbium simulates the action of calcium on electrophysiological activity in the isolated fish retina.

It has been suggested that terbium (Tb) could be substituted for calcium (Ca) in biological tissue and, because of its useful spectroscopic properties, provide an assessment of calcium distribution in the tissue. In order to assess their physiological effects, we have examined the action of free terbium ions on the membrane potential and light-evoked responses of horizontal cells, and on the massed light evoked response (ERG) of the neural retina. Measurements were performed by intracellular and extracellular recording from the isolated fish retina, superfused with Ringers of various ionic compositions, and certain technical difficulties which occurred in the use of terbium are discussed. We show that Tb ions mimic Ca ions in suppression of the ERG and in hyperpolarization of the horizontal cell membrane potential. The effects of Tb persist after its removal from the superfusate for a longer period than do those of calcium, which indicates that terbium binds more firmly at its site(s) activity. Tb and Ca both suppress the light-evoked S-potentials from the horizontal cells, although some differences were observed in the waveform of the S-potentials during the onset of suppression. We conclude that the physiological effects of Tb on the retina are essentially similar to those of Ca, and that Tb could, therefore, prove a useful marker of Ca distribution in neural tissue.

Animals↗