Prolonged survivals after partial hepatectomies and second-look procedures for primary and secondary carcinoma of the liver.
Explore the source record for details and available documents.
Adult↗
Biomedical subjects
S R Friesen
Publications and source records attributed to S R Friesen.
Embryologic concepts in the APUD system.
The amalgamation of the neural and endocrine physiologic mechanisms for functional homeostasis as a neuroendocrine system is brought into focus in this chapter on the embryologic concepts in the APUD system. The neuroendocrine system, now regarded as the third division of the nervous system, is a regulatory mechanism that links the functions of the autonomic nerves and the endocrine cells throughout the body. The current realization that both neural and endocrine actions are often involved in the clinical manifestations of many syndromes is clarified by the theories on the embryologic origin of the APUD system described here. Relevant historical developments, as well as cytochemical discoveries, have been gradually integrated into the evolving theories of the embryologic origin of the APUD system. These theories have not been without controversy, but new developments stimulate new concepts and, as new investigative tools have produced a plethora of new information that continues to push investigators, basic and clinical into new horizons, earlier theories have been modified and new theories have been developed. These theories are reviewed in chronological order in this chapter.
APUD Cells↗
Review of the neuromuscular abnormalities in achalasia of the esophagus, congenital pyloric stenosis and congenital aganglionic megacolon.
Explore the source record for details and available documents.
Autonomic Nervous System↗
New concepts of the pathogenesis and treatment of non beta islet cell carcinoma of the pancreas.
Explore the source record for details and available documents.
Duodenal Ulcer↗