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S R Malthouse

Publications and source records attributed to S R Malthouse.

6 recordsLinked to original sources
PubMed1993

Radiographic patterns of intrathoracic disease in breast carcinoma: prognostic implications.

The chest radiographic appearances of patients with intrathoracic metastases from breast cancer are variable and their relationship to patient outcome is unknown. This study aimed to classify and determine the frequency of various radiographic patterns and, in addition, to establish whether these patterns can be used to predict patient prognosis. A retrospective study was made of the patients of a major breast unit who over a 3 year period were found to have developed intrathoracic metastases. In each case, the earliest plain chest X-ray showing signs of metastasis was reviewed and the frequency of the different radiographic patterns determined. Comparison was made between these patterns and patient mortality. The chest radiographs of 92 patients who developed intrathoracic metastases during a 3 year period were analysed. Pulmonary nodules were found in 66%, pleural effusions in 41% (bilateral in 18%), lymphadenopathy in 25%, lymphangitis in 18% and pleurally-based nodules in 11%. Median survival of the whole group was 13.5 months. Patients with bilateral, but not unilateral, effusions had a significantly poorer prognosis (median survival 3 months). Although the median survival of patients with lymphangitis seemed poor (5.5 months), this difference was not statistically significant. Multivariate analysis showed bilateral effusions to be the only independent predictor of worse outcome. We have found that of the plain radiographic patterns seen in intrathoracic metastasis from breast cancer, only bilateral pleural effusions can be used to predict a worse prognosis than that associated with intrathoracic metastasis as a whole.

Adult↗
PubMed1992

Ultrasonic and computed tomographic appearances of paraganglioma simulating pancreatic mass.

We report two cases of paraganglioma in which the tumour was situated adjacent to the head of the pancreas simulating a pancreatic mass lesion. The absence of biliary or pancreatic duct dilatation on ultrasound in the presence of a large mass suggested a retroperitoneal tumour rather than a pancreatic adenocarcinoma. Functional activity in these tumours is common and should be excluded before biopsy.

Diagnosis, Differential↗
PubMed1992

Multiple myeloma: appearance at MR imaging.

Magnetic resonance (MR) imaging examinations of the lumbar spine and clinical and laboratory findings in 32 patients with multiple myeloma were reviewed. On T1-weighted images, signal intensity (SI) of the vertebrae approximated that of muscle in 14 cases and was intermediate (between the SIs of muscle and fat) in 18. Definite foci of decreased SI were seen in eight cases (25%), and foci of increased SI, representing fatty infiltration, were seen in 12 (38%). On T2-weighted images, SI approximated that of muscle in 17 cases and was intermediate in 15. Definite foci of increased SI were seen in 17 (53%). Of 38 vertebral compression fractures (including 18 in nine additional patients), foci of abnormal SI consistent with tumor on either T1- or T2-weighted images were seen in 19 cases (50%). There was no correlation between MR imaging findings and laboratory or bone marrow findings. Foci of presumed tumor were better or exclusively shown on T2-weighted images in 11 of 17 patients (65%) with identifiable focal disease. Other suggestions of multiple myeloma on T1-weighted images may be the absence of fatty replacement or a generalized decrease in SI.

Female↗
PubMed1991

Primary renal carcinoid--case report.

Carcinoid tumour is a rare cause of a renal mass. Only fourteen cases have been reported since it was first described in 1966. This case illustrates most of the commoner features.

Carcinoid Tumor↗
PubMedDate not supplied

Computerised tomography scans of the head in a district general hospital.

We report the results of a retrospective study of all computerised tomography (CT) brain scans of adult patients carried out over a 10-week period, based on radiological and clinical records. The commonest scan results were normal (51%) and stroke (26%), with an overall diagnostic accuracy of 43/80 (54%). On the basis of a retrospective blind survey by a neurologist, 42% of scans were thought not to be indicated. The results indicate the need for: guidelines on the use of CT scanning in stroke. Emphasis of current guidelines on the use of CT scanning in head injury. Neurological assessment of some suspected diagnoses before scanning.

Adult↗